An Adolescent Female with Bipolar Disorder Presenting with Lithium-Induced Hyperthyroidism
Lithium therapy has been associated with several endocrine disorders including thyroid dysfunction, diabetes insipidus, and hyperparathyroidism. While its suppressive effect on thyroid function is well known, it is very rare to observe lithium-induced hyperthyroidism especially in the pediatric popu...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Case Reports in Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2020/1283464 |
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| author | Pratibha Rana Patria Alba Aponte Ghufran Babar |
| author_facet | Pratibha Rana Patria Alba Aponte Ghufran Babar |
| author_sort | Pratibha Rana |
| collection | DOAJ |
| description | Lithium therapy has been associated with several endocrine disorders including thyroid dysfunction, diabetes insipidus, and hyperparathyroidism. While its suppressive effect on thyroid function is well known, it is very rare to observe lithium-induced hyperthyroidism especially in the pediatric population. Here, we describe a case of lithium-induced hyperthyroidism in an adolescent female with bipolar disorder. The patient is a 17-year-old female who was treated with lithium for bipolar disorder and presented with symptoms and laboratory findings consistent with hyperthyroidism. Since thyroid autoantibodies were negative, thyroid dysfunction was attributed to lithium toxicity. Indeed, her clinical and biochemical hyperthyroid state resolved after stopping lithium therapy. Lithium-associated hyperthyroidism can occur in the pediatric population. We propose close monitoring of thyroid hormone levels in children on lithium therapy. |
| format | Article |
| id | doaj-art-10686e811b414821b9b171665c6cece0 |
| institution | Kabale University |
| issn | 2090-6501 2090-651X |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Endocrinology |
| spelling | doaj-art-10686e811b414821b9b171665c6cece02025-02-03T06:43:51ZengWileyCase Reports in Endocrinology2090-65012090-651X2020-01-01202010.1155/2020/12834641283464An Adolescent Female with Bipolar Disorder Presenting with Lithium-Induced HyperthyroidismPratibha Rana0Patria Alba Aponte1Ghufran Babar2Children’s Mercy Hospital, 3101 Broadway Blvd., Kansas City, MO 64111, USAChildren’s Mercy Hospital, 3101 Broadway Blvd., Kansas City, MO 64111, USADepartment of Pediatric Endocrinology, Children’s Mercy Hospital, 3101 Broadway Blvd., Kansas City, MO 64111, USALithium therapy has been associated with several endocrine disorders including thyroid dysfunction, diabetes insipidus, and hyperparathyroidism. While its suppressive effect on thyroid function is well known, it is very rare to observe lithium-induced hyperthyroidism especially in the pediatric population. Here, we describe a case of lithium-induced hyperthyroidism in an adolescent female with bipolar disorder. The patient is a 17-year-old female who was treated with lithium for bipolar disorder and presented with symptoms and laboratory findings consistent with hyperthyroidism. Since thyroid autoantibodies were negative, thyroid dysfunction was attributed to lithium toxicity. Indeed, her clinical and biochemical hyperthyroid state resolved after stopping lithium therapy. Lithium-associated hyperthyroidism can occur in the pediatric population. We propose close monitoring of thyroid hormone levels in children on lithium therapy.http://dx.doi.org/10.1155/2020/1283464 |
| spellingShingle | Pratibha Rana Patria Alba Aponte Ghufran Babar An Adolescent Female with Bipolar Disorder Presenting with Lithium-Induced Hyperthyroidism Case Reports in Endocrinology |
| title | An Adolescent Female with Bipolar Disorder Presenting with Lithium-Induced Hyperthyroidism |
| title_full | An Adolescent Female with Bipolar Disorder Presenting with Lithium-Induced Hyperthyroidism |
| title_fullStr | An Adolescent Female with Bipolar Disorder Presenting with Lithium-Induced Hyperthyroidism |
| title_full_unstemmed | An Adolescent Female with Bipolar Disorder Presenting with Lithium-Induced Hyperthyroidism |
| title_short | An Adolescent Female with Bipolar Disorder Presenting with Lithium-Induced Hyperthyroidism |
| title_sort | adolescent female with bipolar disorder presenting with lithium induced hyperthyroidism |
| url | http://dx.doi.org/10.1155/2020/1283464 |
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