Primary Splenic Leiomyosarcoma With Metastasis in a Rhesus Monkey (Macaca mulatta)

ABSTRACT Primary mesenchymal tumours of the spleen in non‐human primates are exceedingly rare. We report on a 13‐year‐old female rhesus monkey who had an enlarged liver, spleen and multiple lung masses. Macroscopic, microscopic and immunohistochemical examinations revealed a splenic leiomyosarcoma w...

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Main Author: Matthew F. Starost
Format: Article
Language:English
Published: Wiley 2025-05-01
Series:Veterinary Medicine and Science
Subjects:
Online Access:https://doi.org/10.1002/vms3.70378
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author Matthew F. Starost
author_facet Matthew F. Starost
author_sort Matthew F. Starost
collection DOAJ
description ABSTRACT Primary mesenchymal tumours of the spleen in non‐human primates are exceedingly rare. We report on a 13‐year‐old female rhesus monkey who had an enlarged liver, spleen and multiple lung masses. Macroscopic, microscopic and immunohistochemical examinations revealed a splenic leiomyosarcoma with widespread metastasis. This is the first report of a splenic leiomyosarcoma in a non‐human primate.
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spelling doaj-art-1064ab19eaac4ef08fa59da3e3a51a0d2025-08-20T03:12:08ZengWileyVeterinary Medicine and Science2053-10952025-05-01113n/an/a10.1002/vms3.70378Primary Splenic Leiomyosarcoma With Metastasis in a Rhesus Monkey (Macaca mulatta)Matthew F. Starost0Office of Research Services Division of Veterinary Resources National Institutes of Health Bethesda Maryland USAABSTRACT Primary mesenchymal tumours of the spleen in non‐human primates are exceedingly rare. We report on a 13‐year‐old female rhesus monkey who had an enlarged liver, spleen and multiple lung masses. Macroscopic, microscopic and immunohistochemical examinations revealed a splenic leiomyosarcoma with widespread metastasis. This is the first report of a splenic leiomyosarcoma in a non‐human primate.https://doi.org/10.1002/vms3.70378rhesus macaquesmooth muscle neoplasmspleen
spellingShingle Matthew F. Starost
Primary Splenic Leiomyosarcoma With Metastasis in a Rhesus Monkey (Macaca mulatta)
Veterinary Medicine and Science
rhesus macaque
smooth muscle neoplasm
spleen
title Primary Splenic Leiomyosarcoma With Metastasis in a Rhesus Monkey (Macaca mulatta)
title_full Primary Splenic Leiomyosarcoma With Metastasis in a Rhesus Monkey (Macaca mulatta)
title_fullStr Primary Splenic Leiomyosarcoma With Metastasis in a Rhesus Monkey (Macaca mulatta)
title_full_unstemmed Primary Splenic Leiomyosarcoma With Metastasis in a Rhesus Monkey (Macaca mulatta)
title_short Primary Splenic Leiomyosarcoma With Metastasis in a Rhesus Monkey (Macaca mulatta)
title_sort primary splenic leiomyosarcoma with metastasis in a rhesus monkey macaca mulatta
topic rhesus macaque
smooth muscle neoplasm
spleen
url https://doi.org/10.1002/vms3.70378
work_keys_str_mv AT matthewfstarost primarysplenicleiomyosarcomawithmetastasisinarhesusmonkeymacacamulatta