The Comparison of Microbiologic Pattern in Chronic Osteomyelitis Over 5 Years Period, Hayatabad Medical Complex, Peshawar
OBJECTIVES This study aimed to quantify the changes in microbiological patterns associated with chronic osteomyelitis over five years. It specifically focused on infections caused by multi-drug resistant (MDR) bacteria and the susceptibility of antimicrobial treatments in the Department of Orthop...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Gandhara University
2025-03-01
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| Series: | Journal of Gandhara Medical and Dental Sciences |
| Subjects: | |
| Online Access: | http://jgmds.org.pk/index.php/JGMDS/article/view/675 |
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| Summary: | OBJECTIVES
This study aimed to quantify the changes in microbiological patterns associated with chronic osteomyelitis over five years. It specifically focused on infections caused by multi-drug resistant (MDR) bacteria and the susceptibility of antimicrobial treatments in the Department of Orthopedic and Spine at HMC, Peshawar.
METHODOLOGY
This cross-sectional study was conducted in the Department of Orthopedic & Spine Surgery Hayatabad Medical Complex Peshawar, Pakistan, from 1st August 2023 to 31st July 2024. The sample size was 133. A non-probability consecutive sampling technique was used for sampling. All patients fulfilling the inclusion criteria were included in our study. Patient’s age (< 45 years or > 45 years) & gender (men/women) were our demographic variables, while the presence of chronic osteomyelitis was our research variable. Data was analyzed using IBM-SPSS-V.25.
RESULTS
Out of 134 patients in the study, 70(52.2%) were males & 64(47.8%) were females. Among patients in Group A, i.e., from 11th Nov 2018 to 1st Nov 2019, the most prevalent microbe causing osteomyelitis was Pseudomonas aeruginosa, 29%, followed by MRSA found in 26.3%. Among patients in Group B, i.e., 1st Nov 2023 to 1st Nov 2024, the most prevalent microbe causing osteomyelitis was Methicillin Sensitive Staph aureus (MSSA) 40.2% followed by Pseudomonas aeruginosa 13.8%. MRSA was isolated from 2 cases. Among instances of various osteomyelitis, E-Coli & Pseudomonas aeruginosa were the most resistant microbes to multiple antibiotics.
CONCLUSION
The evolving antibiotic resistance to various microbes has made it mandatory to perform cultures of infected bone & to use antibiotics that are sensitive to specific organisms. Further, in our setup, there has been a decline in several MRSA cases in 5-year period causing osteomyelitis. Pseudomonas aeruginosa & E-Coli are associated with multi-drug-resistant Chronic Osteomyelitis.
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| ISSN: | 2312-9433 2618-1452 |