Transcranial sonography as a diagnostic tool for Parkinson's disease: a pilot study in the city of Rio de Janeiro, Brazil
In Brazil there is no systematic study on Transcranial Sonography (TCS), a neuroimaging method that depicts echogenic deep brain structures using ultrasound. OBJECTIVE: To establish the percentage of subjects with permissive temporal windows and to address the ability of TCS of the substantia nigra...
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Thieme Revinter Publicações
2011-12-01
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| Series: | Arquivos de Neuro-Psiquiatria |
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| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2011000700008&lng=en&tlng=en |
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| author | Rita de Cássia Leite Fernandes Ana Lucia Zuma de Rosso Maurice Borges Vincent Kátia Silveira da Silva Claudia Bonan Nordeval Cavalcante Araújo Daniela Berg |
| author_facet | Rita de Cássia Leite Fernandes Ana Lucia Zuma de Rosso Maurice Borges Vincent Kátia Silveira da Silva Claudia Bonan Nordeval Cavalcante Araújo Daniela Berg |
| author_sort | Rita de Cássia Leite Fernandes |
| collection | DOAJ |
| description | In Brazil there is no systematic study on Transcranial Sonography (TCS), a neuroimaging method that depicts echogenic deep brain structures using ultrasound. OBJECTIVE: To establish the percentage of subjects with permissive temporal windows and to address the ability of TCS of the substantia nigra (SN) to distinguish parkinsonian patients in a Brazilian sample. METHOD: We performed TCS using the Acuson X300 (Siemens, Germany) in 37 individuals: 23 with Parkinson's disease (PD) and 14 healthy controls. RESULTS: 10.8% of subjects had insufficient temporal acoustic bone windows. SN echogenic areas were larger in patients (mean±SD, 0.31±0.08cm²) compared to controls (mean±SD, 0.17±0.02cm²). TCS accurately identified 88.2% of PD patients. CONCLUSION: A large proportion of Brazilians seem to be eligible for TCS. An expressive number of PD patients could be diagnosed by TCS based on an expanded SN echogenic area. However, the current data is preliminary and must be corroborated by larger studies. |
| format | Article |
| id | doaj-art-104d4fe5fd58424b982935e9cbda7f5a |
| institution | Kabale University |
| issn | 1678-4227 |
| language | English |
| publishDate | 2011-12-01 |
| publisher | Thieme Revinter Publicações |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj-art-104d4fe5fd58424b982935e9cbda7f5a2025-08-20T03:55:44ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-42272011-12-0169689289510.1590/S0004-282X2011000700008S0004-282X2011000700008Transcranial sonography as a diagnostic tool for Parkinson's disease: a pilot study in the city of Rio de Janeiro, BrazilRita de Cássia Leite Fernandes0Ana Lucia Zuma de Rosso1Maurice Borges Vincent2Kátia Silveira da Silva3Claudia Bonan4Nordeval Cavalcante Araújo5Daniela Berg6Universidade Federal do Rio de JaneiroUniversidade Federal do Rio de JaneiroUniversidade Federal do Rio de JaneiroFundação Oswaldo CruzFundação Oswaldo CruzUniversidade Federal do Rio de JaneiroEberhard Karls Universität TübingenIn Brazil there is no systematic study on Transcranial Sonography (TCS), a neuroimaging method that depicts echogenic deep brain structures using ultrasound. OBJECTIVE: To establish the percentage of subjects with permissive temporal windows and to address the ability of TCS of the substantia nigra (SN) to distinguish parkinsonian patients in a Brazilian sample. METHOD: We performed TCS using the Acuson X300 (Siemens, Germany) in 37 individuals: 23 with Parkinson's disease (PD) and 14 healthy controls. RESULTS: 10.8% of subjects had insufficient temporal acoustic bone windows. SN echogenic areas were larger in patients (mean±SD, 0.31±0.08cm²) compared to controls (mean±SD, 0.17±0.02cm²). TCS accurately identified 88.2% of PD patients. CONCLUSION: A large proportion of Brazilians seem to be eligible for TCS. An expressive number of PD patients could be diagnosed by TCS based on an expanded SN echogenic area. However, the current data is preliminary and must be corroborated by larger studies.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2011000700008&lng=en&tlng=endiagnóstico por imagemultrassonografiadoença de Parkinson |
| spellingShingle | Rita de Cássia Leite Fernandes Ana Lucia Zuma de Rosso Maurice Borges Vincent Kátia Silveira da Silva Claudia Bonan Nordeval Cavalcante Araújo Daniela Berg Transcranial sonography as a diagnostic tool for Parkinson's disease: a pilot study in the city of Rio de Janeiro, Brazil Arquivos de Neuro-Psiquiatria diagnóstico por imagem ultrassonografia doença de Parkinson |
| title | Transcranial sonography as a diagnostic tool for Parkinson's disease: a pilot study in the city of Rio de Janeiro, Brazil |
| title_full | Transcranial sonography as a diagnostic tool for Parkinson's disease: a pilot study in the city of Rio de Janeiro, Brazil |
| title_fullStr | Transcranial sonography as a diagnostic tool for Parkinson's disease: a pilot study in the city of Rio de Janeiro, Brazil |
| title_full_unstemmed | Transcranial sonography as a diagnostic tool for Parkinson's disease: a pilot study in the city of Rio de Janeiro, Brazil |
| title_short | Transcranial sonography as a diagnostic tool for Parkinson's disease: a pilot study in the city of Rio de Janeiro, Brazil |
| title_sort | transcranial sonography as a diagnostic tool for parkinson s disease a pilot study in the city of rio de janeiro brazil |
| topic | diagnóstico por imagem ultrassonografia doença de Parkinson |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2011000700008&lng=en&tlng=en |
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