Potential Role of CREM in Diabetes‐Associated Testicular Dysfunction: Current Evidence and Future Perspectives

Potential Role of CREM in Diabetes‐Associated Testicular Dysfunction: Current Evidence and Future Perspectives

ABSTRACT Background Type 2 diabetes mellitus (T2D) is a growing metabolic disorder affecting all age groups and is linked to testiculopathy, a key contributor to male infertility. Testiculopathy disrupts spermatogenesis and the sperm microenvironment, with the cyclic adenosine monophosphate (cAMP) r...

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Main Authors: Olabimpe Caroline Badejogbin, Oyedayo Phillips Akano, Oluwafisayo Elizabeth Boluwatife Julius, Mary Olaoluwa Agunloye, Makinde Vincent Olubiyi, Ojichukwuka Ebere Chijioke‐Agu, Matthew Agene Obekpa, Adesina Paul Arikawe, Kehinde Samuel Olaniyi
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Reproductive Medicine and Biology
Subjects:
CREM
male infertility
reproduction
spermatogenesis
testiculopathy
type 2 diabetes mellitus
Online Access:https://doi.org/10.1002/rmb2.12661
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