Functional ultrasound imaging and prewhitening analysis reveal MK-801-induced disruption of brain network connectivity

Functional ultrasound imaging and prewhitening analysis reveal MK-801-induced disruption of brain network connectivity

BackgroundDisruption of N-methyl-D-aspartate receptor (NMDAR) activity within the septohippocampal network - a critical circuit that includes the hippocampus, medial prefrontal cortex (mPFC) and other nuclei - is believed to contribute to learning and memory impairments. Although animal models using...

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Bibliographic Details
Main Authors: Erik Hakopian, Argishti E. Stepanian, Shan Zhong, Kofi A. Agyeman, Nancy Zepeda, Kevin Wu, Charles Liu, Darrin J. Lee, Vassilios Christopoulos
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Pharmacology
Subjects:
functional ultrasound imaging (fUSI)
brain network connectivity
prewhitening analysis
MK-801
NMDAR inhibition
memory
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1562102/full
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