Rapidly Progressive Erosive Arthritis: A Case of Multicentric Reticulohistiocytosis Emphasizing Radiographic Progression, Ultrasound Features, and Efficacious Treatment
We present a case of multicentric reticulohistiocytosis (MRH) in an African American man with both axial and peripheral articular involvement in the absence of typical cutaneous features. Spinal involvement is ill-defined in MRH. This case illustrates spinal lesions as well as the aggressive joint d...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
American College of Physicians
2025-02-01
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| Series: | Annals of Internal Medicine: Clinical Cases |
| Online Access: | https://www.acpjournals.org/doi/10.7326/aimcc.2024.0514 |
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| Summary: | We present a case of multicentric reticulohistiocytosis (MRH) in an African American man with both axial and peripheral articular involvement in the absence of typical cutaneous features. Spinal involvement is ill-defined in MRH. This case illustrates spinal lesions as well as the aggressive joint destruction, bony fragmentation, and inflammatory changes through a series of radiographs of the hand and musculoskeletal ultrasound images. Combination therapy with corticosteroids, methotrexate, adalimumab, and zoledronic acid was effective and led to marked clinical improvement. |
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| ISSN: | 2767-7664 |