Assessing post-COVID-19 functional recovery in healthcare workers: Insights from the 6-minute walking test and DLCO analysis

Introduction: The COVID-19 pandemic has impacted healthcare workers (HCWs) worldwide, necessitating an understanding of its effects on their health and functional capacity. This study utilized the 6-Minute Walk Test (6MWT) and pulmonary function test (PFT) to evaluate post-infection recovery of HCWs...

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Main Authors: Salma AlBahrani, Ali AlBarrak, Jaber S. Alqahtani, Nawal AlGubaisi, Hamoud Alkurdi, Dalia Alburaiki, Abdulrahaman AlGhamdi, Mohammed AlOthaiqy, Osama Faqihi, Meshael Musaed Almershad, Fatimah Hassan Hakami, Asmaa AlAbbadi, Mariam Hassan Hakami, Alaa AlMaimouni, Zechariah Jebakumar Arulanantham, Jaffar A. Al-Tawfiq
Format: Article
Language:English
Published: Elsevier 2025-03-01
Series:Journal of Infection and Public Health
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Online Access:http://www.sciencedirect.com/science/article/pii/S1876034125000139
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author Salma AlBahrani
Ali AlBarrak
Jaber S. Alqahtani
Nawal AlGubaisi
Hamoud Alkurdi
Dalia Alburaiki
Abdulrahaman AlGhamdi
Mohammed AlOthaiqy
Osama Faqihi
Meshael Musaed Almershad
Fatimah Hassan Hakami
Asmaa AlAbbadi
Mariam Hassan Hakami
Alaa AlMaimouni
Zechariah Jebakumar Arulanantham
Jaffar A. Al-Tawfiq
author_facet Salma AlBahrani
Ali AlBarrak
Jaber S. Alqahtani
Nawal AlGubaisi
Hamoud Alkurdi
Dalia Alburaiki
Abdulrahaman AlGhamdi
Mohammed AlOthaiqy
Osama Faqihi
Meshael Musaed Almershad
Fatimah Hassan Hakami
Asmaa AlAbbadi
Mariam Hassan Hakami
Alaa AlMaimouni
Zechariah Jebakumar Arulanantham
Jaffar A. Al-Tawfiq
author_sort Salma AlBahrani
collection DOAJ
description Introduction: The COVID-19 pandemic has impacted healthcare workers (HCWs) worldwide, necessitating an understanding of its effects on their health and functional capacity. This study utilized the 6-Minute Walk Test (6MWT) and pulmonary function test (PFT) to evaluate post-infection recovery of HCWs, and analyzed the results in relation to comorbidities, symptoms, and healthcare admission. Methods: HCWs who previously tested positive for SARS-CoV-2 were recruited, and the 6MWT and PFT were conducted. Clinical data, including comorbidities, symptoms, hospitalization history, intensive care unit (ICU) admission, and mechanical ventilation, were collected. Binary logistic regression analysis and Fisher's exact test were employed to examine the associations between these factors and diffusing capacity of the lungs for carbon monoxide (DLCO) and the 6MWT. Results: The study comprised 80 HCWs, with various comorbidities and various presenting symptoms. On average, 167.24 days (± 63.83 days) post-SARS-CoV-2 infection, 34 (42.5 %) had a DLCO% < 80 % of the predicted value, while 46 (57.5 %) had a DLCO% of ≥ 80 %. The mean six-minute-walk distance (6MWD) was 400.6 ± 54.1 m. No significant associations were found between DLCO% and most of the factors examined, except for Forced Expiratory Flow 25–75 % (FEF25–75 %), although this was not statistically significant (P=0.069). Conclusion: The study provides significant data regarding the functional recovery of HCWs who have recovered from COVID-19 using the 6MWT. Importantly, the findings demonstrated that SARS-CoV-2 infection did not substantially impair the pulmonary functional capacity of HCWs.
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spelling doaj-art-102d653eb3da4624a5da9cdf158577f32025-08-20T02:14:56ZengElsevierJournal of Infection and Public Health1876-03412025-03-0118310266410.1016/j.jiph.2025.102664Assessing post-COVID-19 functional recovery in healthcare workers: Insights from the 6-minute walking test and DLCO analysisSalma AlBahrani0Ali AlBarrak1Jaber S. Alqahtani2Nawal AlGubaisi3Hamoud Alkurdi4Dalia Alburaiki5Abdulrahaman AlGhamdi6Mohammed AlOthaiqy7Osama Faqihi8Meshael Musaed Almershad9Fatimah Hassan Hakami10Asmaa AlAbbadi11Mariam Hassan Hakami12Alaa AlMaimouni13Zechariah Jebakumar Arulanantham14Jaffar A. Al-Tawfiq15Infectious Disease Unit, Specialty Internal Medicine, King Fahd Military Medical Complex, Dhahran, College of medicine-Imam Abdulrahaman Bin Faisal University, Dammam, Saudi ArabiaInfectious disease division, Internal Medicine Department, Prince Sultan Military Medical City, Riyadh, Saudi ArabiaDepartment of Respiratory Care, Prince Sultan Military College of Health Sciences, Dammam, Saudi ArabiaInternal Medicine Department, King Fahd Military Medical Complex, Dhahran, Saudi ArabiaRespiratory therapy department, King Fahad Military Medical Complex, Dhahran, Saudi ArabiaRespiratory therapy department, King Fahad Military Medical Complex, Dhahran, Saudi ArabiaRespiratory therapy department, King Fahad Military Medical Complex, Dhahran, Saudi ArabiaRespiratory therapy department, King Fahad Military Medical Complex, Dhahran, Saudi ArabiaRespiratory therapy department, King Fahad Military Medical Complex, Dhahran, Saudi ArabiaInfection Control Department, King Fahad Military Medical Complex, Dhahran, Saudi ArabiaInfection Control Department, King Fahad Military Medical Complex, Dhahran, Saudi ArabiaInfection Control Department, King Fahad Military Medical Complex, Dhahran, Saudi ArabiaNursing Department, King Fahad Military Medical Complex, Dhahran, Saudi ArabiaRadiology Department, King Fahad Military Medical Complex, Dhahran, Saudi ArabiaVice deanship of postgraduate studies and Scientific Research, Prince Sultan Military College of Health Sciences, Dhahran, Saudi ArabiaInfectious Disease Division, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA; Infectious Disease Unit, Specialty Internal Medicine, Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia; Infectious Disease Division, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Correspondence to: Johns Hopkins Aramco Healthcare, Dhahran 31311, Saudi Arabia.Introduction: The COVID-19 pandemic has impacted healthcare workers (HCWs) worldwide, necessitating an understanding of its effects on their health and functional capacity. This study utilized the 6-Minute Walk Test (6MWT) and pulmonary function test (PFT) to evaluate post-infection recovery of HCWs, and analyzed the results in relation to comorbidities, symptoms, and healthcare admission. Methods: HCWs who previously tested positive for SARS-CoV-2 were recruited, and the 6MWT and PFT were conducted. Clinical data, including comorbidities, symptoms, hospitalization history, intensive care unit (ICU) admission, and mechanical ventilation, were collected. Binary logistic regression analysis and Fisher's exact test were employed to examine the associations between these factors and diffusing capacity of the lungs for carbon monoxide (DLCO) and the 6MWT. Results: The study comprised 80 HCWs, with various comorbidities and various presenting symptoms. On average, 167.24 days (± 63.83 days) post-SARS-CoV-2 infection, 34 (42.5 %) had a DLCO% < 80 % of the predicted value, while 46 (57.5 %) had a DLCO% of ≥ 80 %. The mean six-minute-walk distance (6MWD) was 400.6 ± 54.1 m. No significant associations were found between DLCO% and most of the factors examined, except for Forced Expiratory Flow 25–75 % (FEF25–75 %), although this was not statistically significant (P=0.069). Conclusion: The study provides significant data regarding the functional recovery of HCWs who have recovered from COVID-19 using the 6MWT. Importantly, the findings demonstrated that SARS-CoV-2 infection did not substantially impair the pulmonary functional capacity of HCWs.http://www.sciencedirect.com/science/article/pii/S18760341250001396-minute walk testHealthcare workersCOVID-19Functional capacityPost-infection recovery
spellingShingle Salma AlBahrani
Ali AlBarrak
Jaber S. Alqahtani
Nawal AlGubaisi
Hamoud Alkurdi
Dalia Alburaiki
Abdulrahaman AlGhamdi
Mohammed AlOthaiqy
Osama Faqihi
Meshael Musaed Almershad
Fatimah Hassan Hakami
Asmaa AlAbbadi
Mariam Hassan Hakami
Alaa AlMaimouni
Zechariah Jebakumar Arulanantham
Jaffar A. Al-Tawfiq
Assessing post-COVID-19 functional recovery in healthcare workers: Insights from the 6-minute walking test and DLCO analysis
Journal of Infection and Public Health
6-minute walk test
Healthcare workers
COVID-19
Functional capacity
Post-infection recovery
title Assessing post-COVID-19 functional recovery in healthcare workers: Insights from the 6-minute walking test and DLCO analysis
title_full Assessing post-COVID-19 functional recovery in healthcare workers: Insights from the 6-minute walking test and DLCO analysis
title_fullStr Assessing post-COVID-19 functional recovery in healthcare workers: Insights from the 6-minute walking test and DLCO analysis
title_full_unstemmed Assessing post-COVID-19 functional recovery in healthcare workers: Insights from the 6-minute walking test and DLCO analysis
title_short Assessing post-COVID-19 functional recovery in healthcare workers: Insights from the 6-minute walking test and DLCO analysis
title_sort assessing post covid 19 functional recovery in healthcare workers insights from the 6 minute walking test and dlco analysis
topic 6-minute walk test
Healthcare workers
COVID-19
Functional capacity
Post-infection recovery
url http://www.sciencedirect.com/science/article/pii/S1876034125000139
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