Template switching during DNA replication is a prevalent source of adaptive gene amplification

Template switching during DNA replication is a prevalent source of adaptive gene amplification

Copy number variants (CNVs) are an important source of genetic variation underlying rapid adaptation and genome evolution. Whereas point mutation rates vary with genomic location and local DNA features, the role of genome architecture in the formation and evolutionary dynamics of CNVs is poorly unde...

Full description

Saved in:
Bibliographic Details
Main Authors: Julie N Chuong, Nadav Ben Nun, Ina Suresh, Julia Cano Matthews, Titir De, Grace Avecilla, Farah Abdul-Rahman, Nathan Brandt, Yoav Ram, David Gresham
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2025-02-01
Series:eLife
Subjects:
experimental evolution
copy number variation
GAP1
simulation-based inference
Online Access:https://elifesciences.org/articles/98934
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items