Bacteriological profile, antimicrobial susceptibility, and factors associated with urinary tract infection in pregnant women
Introduction: Urinary tract infection (UTI) is a common bacterial complication in pregnancy. The study aimed to estimate the prevalence, risk factors, and bacterial etiology of UTI during pregnancy and determine the efficacy of antimicrobial drugs in treating UTIs. Methodology: Urine specimens an...
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The Journal of Infection in Developing Countries
2024-03-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/18239 |
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| author | Aza B Taha |
| author_facet | Aza B Taha |
| author_sort | Aza B Taha |
| collection | DOAJ |
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Introduction: Urinary tract infection (UTI) is a common bacterial complication in pregnancy. The study aimed to estimate the prevalence, risk factors, and bacterial etiology of UTI during pregnancy and determine the efficacy of antimicrobial drugs in treating UTIs.
Methodology: Urine specimens and clinical data were collected from pregnant women who attended primary health centers in Erbil, Iraq. All specimens were cultured on appropriate media and identified by standard microbiological methods. The pregnant women were grouped into symptomatic UTI group, asymptomatic bacteriuria group, and the control group. The agar dilution method was used to determine antimicrobial susceptibility.
Results: Among the 5,042 pregnant women included in this study, significant bacteriuria was found in 625 (12.40%) of the cases, and 198 (31.68%) had symptomatic UTI, of which 43.59% were diagnosed during the third trimester. Out of the 643 bacteria isolated, 33.28% were symptomatic UTI, of which 43.59% developed during the third trimester. There was a significant difference in the bacterial etiology between symptomatic UTI and asymptomatic bacteriuria (p = 0.002), as well as between cystitis and pyelonephritis (p = 0.017). The most common bacterial species isolated was Escherichia coli, which was susceptible to fosfomycin (100%), meropenem (99.45%), and nitrofurantoin (97.8%).
Conclusions: Pregnant women are more likely to develop UTI in the third trimester. Escherichia coli is the predominant pathogen. The study suggests the use of fosfomycin, meropenem, and nitrofurantoin for the treatment of UTI. No Gram-positive isolates were resistant to daptomycin.
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| format | Article |
| id | doaj-art-1020c0ef582548ccb430ddcefafa2f98 |
| institution | DOAJ |
| issn | 1972-2680 |
| language | English |
| publishDate | 2024-03-01 |
| publisher | The Journal of Infection in Developing Countries |
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| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-1020c0ef582548ccb430ddcefafa2f982025-08-20T02:57:17ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802024-03-01180310.3855/jidc.18239Bacteriological profile, antimicrobial susceptibility, and factors associated with urinary tract infection in pregnant womenAza B Taha0Medical Research Center, Hawler Medical University, Erbil, Kurdistan Region, Iraq Introduction: Urinary tract infection (UTI) is a common bacterial complication in pregnancy. The study aimed to estimate the prevalence, risk factors, and bacterial etiology of UTI during pregnancy and determine the efficacy of antimicrobial drugs in treating UTIs. Methodology: Urine specimens and clinical data were collected from pregnant women who attended primary health centers in Erbil, Iraq. All specimens were cultured on appropriate media and identified by standard microbiological methods. The pregnant women were grouped into symptomatic UTI group, asymptomatic bacteriuria group, and the control group. The agar dilution method was used to determine antimicrobial susceptibility. Results: Among the 5,042 pregnant women included in this study, significant bacteriuria was found in 625 (12.40%) of the cases, and 198 (31.68%) had symptomatic UTI, of which 43.59% were diagnosed during the third trimester. Out of the 643 bacteria isolated, 33.28% were symptomatic UTI, of which 43.59% developed during the third trimester. There was a significant difference in the bacterial etiology between symptomatic UTI and asymptomatic bacteriuria (p = 0.002), as well as between cystitis and pyelonephritis (p = 0.017). The most common bacterial species isolated was Escherichia coli, which was susceptible to fosfomycin (100%), meropenem (99.45%), and nitrofurantoin (97.8%). Conclusions: Pregnant women are more likely to develop UTI in the third trimester. Escherichia coli is the predominant pathogen. The study suggests the use of fosfomycin, meropenem, and nitrofurantoin for the treatment of UTI. No Gram-positive isolates were resistant to daptomycin. https://jidc.org/index.php/journal/article/view/18239UTIantibiotic resistanceEscherichia colipregnantcystitispyelonephritis |
| spellingShingle | Aza B Taha Bacteriological profile, antimicrobial susceptibility, and factors associated with urinary tract infection in pregnant women Journal of Infection in Developing Countries UTI antibiotic resistance Escherichia coli pregnant cystitis pyelonephritis |
| title | Bacteriological profile, antimicrobial susceptibility, and factors associated with urinary tract infection in pregnant women |
| title_full | Bacteriological profile, antimicrobial susceptibility, and factors associated with urinary tract infection in pregnant women |
| title_fullStr | Bacteriological profile, antimicrobial susceptibility, and factors associated with urinary tract infection in pregnant women |
| title_full_unstemmed | Bacteriological profile, antimicrobial susceptibility, and factors associated with urinary tract infection in pregnant women |
| title_short | Bacteriological profile, antimicrobial susceptibility, and factors associated with urinary tract infection in pregnant women |
| title_sort | bacteriological profile antimicrobial susceptibility and factors associated with urinary tract infection in pregnant women |
| topic | UTI antibiotic resistance Escherichia coli pregnant cystitis pyelonephritis |
| url | https://jidc.org/index.php/journal/article/view/18239 |
| work_keys_str_mv | AT azabtaha bacteriologicalprofileantimicrobialsusceptibilityandfactorsassociatedwithurinarytractinfectioninpregnantwomen |