Proteomic insights into COPD pathogenesis and therapeutic targets: a causal analysis of circulating proteins

Proteomic insights into COPD pathogenesis and therapeutic targets: a causal analysis of circulating proteins

BackgroundChronic obstructive pulmonary disease (COPD) is a preventable and treatable condition, yet current therapies do not halt disease progression, highlighting the need for novel treatments. Using an integrated approach combining proteome-wide Mendelian randomization and Bayesian colocalization...

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Bibliographic Details
Main Authors:	Min Luo, Ying Tang, Jing Qiu, Kai Yang, WenJing Dai, EnRong Fang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-05-01
Series:	Frontiers in Medicine
Subjects:	chronic obstructive pulmonary disease (COPD) circulating proteins Mendelian randomization therapeutic targets lifestyle modifications genetic biomarkers
Online Access:	https://www.frontiersin.org/articles/10.3389/fmed.2025.1529495/full
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