Insufficiency of luteal phase defect an assessment of criteria in patients with endocrine forms of infertility

An Insufficiency of the corpus luteum (LPI) is one of the main causes of endocrine forms of infertility and spontaneous loss of the fetus in early pregnancy. Insufficiency of the corpus luteum, and consequently, defective secretory transformation of the endometrium during the second phase of the men...

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Main Author: A. G. Davudova
Format: Article
Language:Russian
Published: IRBIS LLC 2016-06-01
Series:Акушерство, гинекология и репродукция
Subjects:
Online Access:https://www.gynecology.su/jour/article/view/155
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author A. G. Davudova
author_facet A. G. Davudova
author_sort A. G. Davudova
collection DOAJ
description An Insufficiency of the corpus luteum (LPI) is one of the main causes of endocrine forms of infertility and spontaneous loss of the fetus in early pregnancy. Insufficiency of the corpus luteum, and consequently, defective secretory transformation of the endometrium during the second phase of the menstrual cycle, is a direct consequence of violations of folliculogenesis. A comprehensive assessment of the reproductive system prior to initiating therapy allows to develop algorithm of examination of patients, to choose an individual, pathogenetically substantiated treatment strategy, to select the doses and to avoid the possibility of complications. The object of the study is a comprehensive comparative assessment of the reproductive system of patients with impaired function of the corpus luteum suffering from endocrine forms of infertility and optimization criteria for determining the NLF. Materials and Methods: the study involved 170 women, including the control group. During the study was assessed the state of physical, hormonal profile, as well as ultrasound picture of the state of the reproductive system. Results and Conclusion: LPI is a multifactorial condition. Considering the performance levels of progesterone and estradiol, three forms of insufficient of luteal phase were determined and depending on it, the patients received pathogenetically grounded therapy.
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spelling doaj-art-1017c62d66904e4f87dc6caeb4e3134a2025-08-20T03:57:36ZrusIRBIS LLCАкушерство, гинекология и репродукция2313-73472500-31942016-06-0192243010.17749/2070-4968.2015.9.2.024-030153Insufficiency of luteal phase defect an assessment of criteria in patients with endocrine forms of infertilityA. G. Davudova0First Moscow State Medical Sechenov University of the Ministry of Health Russian FederationAn Insufficiency of the corpus luteum (LPI) is one of the main causes of endocrine forms of infertility and spontaneous loss of the fetus in early pregnancy. Insufficiency of the corpus luteum, and consequently, defective secretory transformation of the endometrium during the second phase of the menstrual cycle, is a direct consequence of violations of folliculogenesis. A comprehensive assessment of the reproductive system prior to initiating therapy allows to develop algorithm of examination of patients, to choose an individual, pathogenetically substantiated treatment strategy, to select the doses and to avoid the possibility of complications. The object of the study is a comprehensive comparative assessment of the reproductive system of patients with impaired function of the corpus luteum suffering from endocrine forms of infertility and optimization criteria for determining the NLF. Materials and Methods: the study involved 170 women, including the control group. During the study was assessed the state of physical, hormonal profile, as well as ultrasound picture of the state of the reproductive system. Results and Conclusion: LPI is a multifactorial condition. Considering the performance levels of progesterone and estradiol, three forms of insufficient of luteal phase were determined and depending on it, the patients received pathogenetically grounded therapy.https://www.gynecology.su/jour/article/view/155luteal phase defectlpdinfertilityreproductive endocrinologystimulation of ovulation
spellingShingle A. G. Davudova
Insufficiency of luteal phase defect an assessment of criteria in patients with endocrine forms of infertility
Акушерство, гинекология и репродукция
luteal phase defect
lpd
infertility
reproductive endocrinology
stimulation of ovulation
title Insufficiency of luteal phase defect an assessment of criteria in patients with endocrine forms of infertility
title_full Insufficiency of luteal phase defect an assessment of criteria in patients with endocrine forms of infertility
title_fullStr Insufficiency of luteal phase defect an assessment of criteria in patients with endocrine forms of infertility
title_full_unstemmed Insufficiency of luteal phase defect an assessment of criteria in patients with endocrine forms of infertility
title_short Insufficiency of luteal phase defect an assessment of criteria in patients with endocrine forms of infertility
title_sort insufficiency of luteal phase defect an assessment of criteria in patients with endocrine forms of infertility
topic luteal phase defect
lpd
infertility
reproductive endocrinology
stimulation of ovulation
url https://www.gynecology.su/jour/article/view/155
work_keys_str_mv AT agdavudova insufficiencyoflutealphasedefectanassessmentofcriteriainpatientswithendocrineformsofinfertility