Maggots: Antimicrobial Stewards and Life Savers

Maggots have been used in wound care for centuries. Their larvae secrete digestive enzymes and antimicrobial compounds that reduce the bacterial load within a wound and promote the growth of new, healthy tissue. We will discuss a series of patients with complex, nonhealing and life-threatening sacra...

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Main Authors: Caitlin Trottier, Shamsuddin Anwar, Lisa Baxter, Natalie Nierenberg
Format: Article
Language:English
Published: American College of Physicians 2024-01-01
Series:Annals of Internal Medicine: Clinical Cases
Online Access:https://www.acpjournals.org/doi/10.7326/aimcc.2023.0693
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author Caitlin Trottier
Shamsuddin Anwar
Lisa Baxter
Natalie Nierenberg
author_facet Caitlin Trottier
Shamsuddin Anwar
Lisa Baxter
Natalie Nierenberg
author_sort Caitlin Trottier
collection DOAJ
description Maggots have been used in wound care for centuries. Their larvae secrete digestive enzymes and antimicrobial compounds that reduce the bacterial load within a wound and promote the growth of new, healthy tissue. We will discuss a series of patients with complex, nonhealing and life-threatening sacral wounds who developed multidrug-resistant sacral osteomyelitis. These wounds had failed to respond to standard and advanced strategies. Medicinal maggots were offered as a last-ditch effort in each case. In addition to saving the patients’ lives, these maggots demonstrated their underappreciated and underused role as antimicrobial stewards.
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institution OA Journals
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publisher American College of Physicians
record_format Article
series Annals of Internal Medicine: Clinical Cases
spelling doaj-art-101776debd5047e2a7fac9d15a8278942025-08-20T02:11:45ZengAmerican College of PhysiciansAnnals of Internal Medicine: Clinical Cases2767-76642024-01-013110.7326/aimcc.2023.0693Maggots: Antimicrobial Stewards and Life SaversCaitlin Trottier0Shamsuddin Anwar1Lisa Baxter2Natalie Nierenberg31Division of Infectious Diseases and Geographic Medicine, Tufts Medical Center, Boston, Massachusetts1Division of Infectious Diseases and Geographic Medicine, Tufts Medical Center, Boston, Massachusetts2Wound Care, Tufts Medical Center, Boston, Massachusetts2Wound Care, Tufts Medical Center, Boston, MassachusettsMaggots have been used in wound care for centuries. Their larvae secrete digestive enzymes and antimicrobial compounds that reduce the bacterial load within a wound and promote the growth of new, healthy tissue. We will discuss a series of patients with complex, nonhealing and life-threatening sacral wounds who developed multidrug-resistant sacral osteomyelitis. These wounds had failed to respond to standard and advanced strategies. Medicinal maggots were offered as a last-ditch effort in each case. In addition to saving the patients’ lives, these maggots demonstrated their underappreciated and underused role as antimicrobial stewards.https://www.acpjournals.org/doi/10.7326/aimcc.2023.0693
spellingShingle Caitlin Trottier
Shamsuddin Anwar
Lisa Baxter
Natalie Nierenberg
Maggots: Antimicrobial Stewards and Life Savers
Annals of Internal Medicine: Clinical Cases
title Maggots: Antimicrobial Stewards and Life Savers
title_full Maggots: Antimicrobial Stewards and Life Savers
title_fullStr Maggots: Antimicrobial Stewards and Life Savers
title_full_unstemmed Maggots: Antimicrobial Stewards and Life Savers
title_short Maggots: Antimicrobial Stewards and Life Savers
title_sort maggots antimicrobial stewards and life savers
url https://www.acpjournals.org/doi/10.7326/aimcc.2023.0693
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AT natalienierenberg maggotsantimicrobialstewardsandlifesavers