Maggots: Antimicrobial Stewards and Life Savers

Maggots have been used in wound care for centuries. Their larvae secrete digestive enzymes and antimicrobial compounds that reduce the bacterial load within a wound and promote the growth of new, healthy tissue. We will discuss a series of patients with complex, nonhealing and life-threatening sacra...

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Bibliographic Details
Main Authors: Caitlin Trottier, Shamsuddin Anwar, Lisa Baxter, Natalie Nierenberg
Format: Article
Language:English
Published: American College of Physicians 2024-01-01
Series:Annals of Internal Medicine: Clinical Cases
Online Access:https://www.acpjournals.org/doi/10.7326/aimcc.2023.0693
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Summary:Maggots have been used in wound care for centuries. Their larvae secrete digestive enzymes and antimicrobial compounds that reduce the bacterial load within a wound and promote the growth of new, healthy tissue. We will discuss a series of patients with complex, nonhealing and life-threatening sacral wounds who developed multidrug-resistant sacral osteomyelitis. These wounds had failed to respond to standard and advanced strategies. Medicinal maggots were offered as a last-ditch effort in each case. In addition to saving the patients’ lives, these maggots demonstrated their underappreciated and underused role as antimicrobial stewards.
ISSN:2767-7664