Topical levocabastine—a review of therapeutic efficacy compared with topical sodium cromoglycate and oral terfenadine on days with high pollen counts
Levocabastine is a new H1-receptor antagonist specifically developed for the topical treatment of seasonal allergic rhinoconjunctivitis. Clinical experience to date clearly demonstrates that levocabastine eye drops and nasal spray are effective and well tolerated for the treatment of this allergic d...
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| Format: | Article |
| Language: | English |
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Wiley
1995-01-01
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| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/S0962935195000809 |
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| _version_ | 1849304470219915264 |
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| author | Marianela de Azevedo |
| author_facet | Marianela de Azevedo |
| author_sort | Marianela de Azevedo |
| collection | DOAJ |
| description | Levocabastine is a new H1-receptor antagonist specifically developed for the topical treatment of seasonal allergic rhinoconjunctivitis. Clinical experience to date clearly demonstrates that levocabastine eye drops and nasal spray are effective and well tolerated for the treatment of this allergic disorder. Analysis of data from a number of comparative trials reveals that topical levocabastine is at least as effective as sodium cromoglycate and the oral antihistamine terfenadine, even on days with high pollen counts (≥ 50 pollen particles/m3 ) when symptoms are severe. Coupled with a rapid onset of action and twice daily dosing, these findings make topical levocabastine an attractive alternative to other therapeutic approaches as a first-line therapy for the treatment, of this common condition. |
| format | Article |
| id | doaj-art-10121dbd39be45239f962f36b6a6b8f8 |
| institution | Kabale University |
| issn | 0962-9351 1466-1861 |
| language | English |
| publishDate | 1995-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Mediators of Inflammation |
| spelling | doaj-art-10121dbd39be45239f962f36b6a6b8f82025-08-20T03:55:44ZengWileyMediators of Inflammation0962-93511466-18611995-01-0147S21S2510.1155/S0962935195000809Topical levocabastine—a review of therapeutic efficacy compared with topical sodium cromoglycate and oral terfenadine on days with high pollen countsMarianela de Azevedo0Serviço de Imunoalergologia, Hospital de S. João, Al Prof Hernâni Monteiro, Porto 4200, PortugalLevocabastine is a new H1-receptor antagonist specifically developed for the topical treatment of seasonal allergic rhinoconjunctivitis. Clinical experience to date clearly demonstrates that levocabastine eye drops and nasal spray are effective and well tolerated for the treatment of this allergic disorder. Analysis of data from a number of comparative trials reveals that topical levocabastine is at least as effective as sodium cromoglycate and the oral antihistamine terfenadine, even on days with high pollen counts (≥ 50 pollen particles/m3 ) when symptoms are severe. Coupled with a rapid onset of action and twice daily dosing, these findings make topical levocabastine an attractive alternative to other therapeutic approaches as a first-line therapy for the treatment, of this common condition.http://dx.doi.org/10.1155/S0962935195000809 |
| spellingShingle | Marianela de Azevedo Topical levocabastine—a review of therapeutic efficacy compared with topical sodium cromoglycate and oral terfenadine on days with high pollen counts Mediators of Inflammation |
| title | Topical levocabastine—a review of therapeutic efficacy compared with topical sodium cromoglycate and oral terfenadine on days with high pollen counts |
| title_full | Topical levocabastine—a review of therapeutic efficacy compared with topical sodium cromoglycate and oral terfenadine on days with high pollen counts |
| title_fullStr | Topical levocabastine—a review of therapeutic efficacy compared with topical sodium cromoglycate and oral terfenadine on days with high pollen counts |
| title_full_unstemmed | Topical levocabastine—a review of therapeutic efficacy compared with topical sodium cromoglycate and oral terfenadine on days with high pollen counts |
| title_short | Topical levocabastine—a review of therapeutic efficacy compared with topical sodium cromoglycate and oral terfenadine on days with high pollen counts |
| title_sort | topical levocabastine a review of therapeutic efficacy compared with topical sodium cromoglycate and oral terfenadine on days with high pollen counts |
| url | http://dx.doi.org/10.1155/S0962935195000809 |
| work_keys_str_mv | AT marianeladeazevedo topicallevocabastineareviewoftherapeuticefficacycomparedwithtopicalsodiumcromoglycateandoralterfenadineondayswithhighpollencounts |