NAT yield in blood donors: An observational study
Introduction: Individual donation nucleic acid testing (ID-NAT) is considered as highly sensitive technology for viral transfusion-transmissible infections (TTIs) in blood donors. The present study was aimed to analyze the results of ID-NAT with special reference to different types of donors, their...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2023-11-01
|
| Series: | Journal of Family Medicine and Primary Care |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/jfmpc.jfmpc_424_23 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850195308909166592 |
|---|---|
| author | Ankit Sharma Sunita Bundas Rashmi Parashar |
| author_facet | Ankit Sharma Sunita Bundas Rashmi Parashar |
| author_sort | Ankit Sharma |
| collection | DOAJ |
| description | Introduction:
Individual donation nucleic acid testing (ID-NAT) is considered as highly sensitive technology for viral transfusion-transmissible infections (TTIs) in blood donors. The present study was aimed to analyze the results of ID-NAT with special reference to different types of donors, their age, gender, blood group ranges in a tertiary care center in north India.
Methodology:
The present study was done from 24th June 2019 to 31st December 2021 in Blood Center, Department of Immunohematology and Blood Transfusion, SMS Hospital, Jaipur. A total of 18313 apparently healthy adult donors were included in present study.
Result:
In 2019 Combined NAT yield was 1 in 754, in 2020 it was 1 in 2368 and in 2021 it was 1 in 741. With Total NAT yield was 1 in 1017 (0.09 %) over a period of study. NAT yield in HBV is 1 in 1077, in HCV 1 in 18313 and no NAT Yield in HIV.
Conclusion:
NAT testing for hepatitis B provides additional safety because ELISA does not pick up occult hepatitis. The non-seroconverting or delayed seroconverting disease is missed by ELISA alone and can be picked up by NAT. |
| format | Article |
| id | doaj-art-1008a2ed522d426ab36e8d182be9cc61 |
| institution | OA Journals |
| issn | 2249-4863 2278-7135 |
| language | English |
| publishDate | 2023-11-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Family Medicine and Primary Care |
| spelling | doaj-art-1008a2ed522d426ab36e8d182be9cc612025-08-20T02:13:47ZengWolters Kluwer Medknow PublicationsJournal of Family Medicine and Primary Care2249-48632278-71352023-11-0112112763276710.4103/jfmpc.jfmpc_424_23NAT yield in blood donors: An observational studyAnkit SharmaSunita BundasRashmi ParasharIntroduction: Individual donation nucleic acid testing (ID-NAT) is considered as highly sensitive technology for viral transfusion-transmissible infections (TTIs) in blood donors. The present study was aimed to analyze the results of ID-NAT with special reference to different types of donors, their age, gender, blood group ranges in a tertiary care center in north India. Methodology: The present study was done from 24th June 2019 to 31st December 2021 in Blood Center, Department of Immunohematology and Blood Transfusion, SMS Hospital, Jaipur. A total of 18313 apparently healthy adult donors were included in present study. Result: In 2019 Combined NAT yield was 1 in 754, in 2020 it was 1 in 2368 and in 2021 it was 1 in 741. With Total NAT yield was 1 in 1017 (0.09 %) over a period of study. NAT yield in HBV is 1 in 1077, in HCV 1 in 18313 and no NAT Yield in HIV. Conclusion: NAT testing for hepatitis B provides additional safety because ELISA does not pick up occult hepatitis. The non-seroconverting or delayed seroconverting disease is missed by ELISA alone and can be picked up by NAT.https://journals.lww.com/10.4103/jfmpc.jfmpc_424_23nat yieldseroyieldtransfusion transmitted infection |
| spellingShingle | Ankit Sharma Sunita Bundas Rashmi Parashar NAT yield in blood donors: An observational study Journal of Family Medicine and Primary Care nat yield seroyield transfusion transmitted infection |
| title | NAT yield in blood donors: An observational study |
| title_full | NAT yield in blood donors: An observational study |
| title_fullStr | NAT yield in blood donors: An observational study |
| title_full_unstemmed | NAT yield in blood donors: An observational study |
| title_short | NAT yield in blood donors: An observational study |
| title_sort | nat yield in blood donors an observational study |
| topic | nat yield seroyield transfusion transmitted infection |
| url | https://journals.lww.com/10.4103/jfmpc.jfmpc_424_23 |
| work_keys_str_mv | AT ankitsharma natyieldinblooddonorsanobservationalstudy AT sunitabundas natyieldinblooddonorsanobservationalstudy AT rashmiparashar natyieldinblooddonorsanobservationalstudy |