SNHG12 downregulation induces follicular dysplasia by modulating the glycolysis of granulosa cell in polycystic ovary syndrome

SNHG12 downregulation induces follicular dysplasia by modulating the glycolysis of granulosa cell in polycystic ovary syndrome

IntroductionPolycystic ovary syndrome (PCOS) is characterized by follicular dysplasia, with granulosa cells (GCs) glycolysis playing a pivotal role in this pathology. Although the involvement of long noncoding RNAs (lncRNAs) in diverse biological processes of PCOS has been well documented, the molec...

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Bibliographic Details
Main Authors: Sisi Yan, Bing Qu, Yu Chen, Qiuji Wu, Jinli Ding, Hui Qiu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
SNHG12
PCOS
granulosa cells
glycolysis
follicular dysplasia
HMGB1
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1585987/full
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