Secondary Histiocytic Sarcoma in a Pre-B-Acute Lymphoblastic Leukemia
Histiocytic sarcoma (HS) is a rare malignancy with grave prognosis. Adult acute lymphoblastic leukemia (ALL) patients developing HS as a secondary malignancy reported in the literature is even rarer. Through our case report, we aim to describe an adult pre-B-ALL patient who subsequently developed ex...
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| Format: | Article |
| Language: | English |
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Thieme Medical and Scientific Publishers Pvt. Ltd.
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| Series: | Indian Journal of Medical and Paediatric Oncology |
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| Online Access: | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1778110 |
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| author | Sharanya Ramakrishnan Vivek Radhakrishnan Aaishwarya Dhabe Mayur Parihar Lateef Zameer Neeraj Arora Reena Nair |
| author_facet | Sharanya Ramakrishnan Vivek Radhakrishnan Aaishwarya Dhabe Mayur Parihar Lateef Zameer Neeraj Arora Reena Nair |
| author_sort | Sharanya Ramakrishnan |
| collection | DOAJ |
| description | Histiocytic sarcoma (HS) is a rare malignancy with grave prognosis. Adult acute lymphoblastic leukemia (ALL) patients developing HS as a secondary malignancy reported in the literature is even rarer. Through our case report, we aim to describe an adult pre-B-ALL patient who subsequently developed extensive HS while on maintenance therapy. We present the course of the disease, the management, and the resultant outcome. Active reporting of the course and management of secondary HS in adult ALL patients need to be emphasized to gain better insight into the presentation and the course of the disease, incidence as well as molecular pathology, especially given the relative silence of the literature in this regard. |
| format | Article |
| id | doaj-art-1001109acce34a41bdf334c0647cb7c9 |
| institution | OA Journals |
| issn | 0971-5851 0975-2129 |
| language | English |
| publisher | Thieme Medical and Scientific Publishers Pvt. Ltd. |
| record_format | Article |
| series | Indian Journal of Medical and Paediatric Oncology |
| spelling | doaj-art-1001109acce34a41bdf334c0647cb7c92025-08-20T02:22:34ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Medical and Paediatric Oncology0971-58510975-212910.1055/s-0043-1778110Secondary Histiocytic Sarcoma in a Pre-B-Acute Lymphoblastic LeukemiaSharanya Ramakrishnan0https://orcid.org/0000-0002-6533-9182Vivek Radhakrishnan1https://orcid.org/0000-0001-9484-5669Aaishwarya Dhabe2Mayur Parihar3Lateef Zameer4Neeraj Arora5https://orcid.org/0000-0002-1739-9455Reena Nair6https://orcid.org/0000-0003-3032-1350Department of Clinical Haematology and Cellular Therapies, Tata Medical Center, Kolkata, West Bengal, IndiaDepartment of Clinical Haematology and Cellular Therapies, Tata Medical Center, Kolkata, West Bengal, IndiaDepartment of Cytogenetics, Tata Medical Center, Kolkata, West Bengal, IndiaDepartment of Cytogenetics & Laboratory Haematology, Tata Medical Center, Kolkata, West Bengal, IndiaDepartment of Pathology, Tata Medical Center, Kolkata, West Bengal, IndiaUnipath Speciality Laboratory, Ahmedabad, Gujarat, IndiaHead, Department of Clinical Hematology and Cellular therapies, Tata Medical Center, Kolkata, West Bengal, IndiaHistiocytic sarcoma (HS) is a rare malignancy with grave prognosis. Adult acute lymphoblastic leukemia (ALL) patients developing HS as a secondary malignancy reported in the literature is even rarer. Through our case report, we aim to describe an adult pre-B-ALL patient who subsequently developed extensive HS while on maintenance therapy. We present the course of the disease, the management, and the resultant outcome. Active reporting of the course and management of secondary HS in adult ALL patients need to be emphasized to gain better insight into the presentation and the course of the disease, incidence as well as molecular pathology, especially given the relative silence of the literature in this regard.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1778110secondary HSadult pre-B-ALLsecondary malignancies |
| spellingShingle | Sharanya Ramakrishnan Vivek Radhakrishnan Aaishwarya Dhabe Mayur Parihar Lateef Zameer Neeraj Arora Reena Nair Secondary Histiocytic Sarcoma in a Pre-B-Acute Lymphoblastic Leukemia Indian Journal of Medical and Paediatric Oncology secondary HS adult pre-B-ALL secondary malignancies |
| title | Secondary Histiocytic Sarcoma in a Pre-B-Acute Lymphoblastic Leukemia |
| title_full | Secondary Histiocytic Sarcoma in a Pre-B-Acute Lymphoblastic Leukemia |
| title_fullStr | Secondary Histiocytic Sarcoma in a Pre-B-Acute Lymphoblastic Leukemia |
| title_full_unstemmed | Secondary Histiocytic Sarcoma in a Pre-B-Acute Lymphoblastic Leukemia |
| title_short | Secondary Histiocytic Sarcoma in a Pre-B-Acute Lymphoblastic Leukemia |
| title_sort | secondary histiocytic sarcoma in a pre b acute lymphoblastic leukemia |
| topic | secondary HS adult pre-B-ALL secondary malignancies |
| url | http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1778110 |
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