Anomalous Left Main Coronary Artery: Case Series of Different Courses and Literature Review
Background. Congenital anomalies of the coronary arteries are a cause of sudden cardiac death. Of the known anatomic variants, anomalous origination of a coronary artery from an opposite sinus of Valsalva (ACAOS) remains the main focus of debate. Case Series. We present three cases, all presenting t...
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| Format: | Article |
| Language: | English |
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Wiley
2013-01-01
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| Series: | Case Reports in Vascular Medicine |
| Online Access: | http://dx.doi.org/10.1155/2013/380952 |
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| author | Adam T. Marler Jamil A. Malik Ahmad M. Slim |
| author_facet | Adam T. Marler Jamil A. Malik Ahmad M. Slim |
| author_sort | Adam T. Marler |
| collection | DOAJ |
| description | Background. Congenital anomalies of the coronary arteries are a cause of sudden cardiac death. Of the known anatomic variants, anomalous origination of a coronary artery from an opposite sinus of Valsalva (ACAOS) remains the main focus of debate. Case Series. We present three cases, all presenting to our facility within one week’s time, of patients with newly discovered anomalous origination of the left coronary artery from the right sinus of Valsalva (L-ACAOS). All patients underwent cardiac computed tomography for evaluation of coronary anatomy along with other forms of functional testing. Despite the high risk nature of two of the anomalies, the patients are being treated medically without recurrence of symptoms. Summary. After review of the literature, we have found that the risk of sudden cardiac death in patients with congenital coronary anomalies, even among variants considered the highest risk, may be overestimated. In addition, the exact prevalence of coronary anomalies in the general population is currently underestimated. A national coronary artery anomaly registry based on cardiac computed tomography and invasive coronary angiography data would be helpful in advancing our understanding of these cardiac peculiarities. The true prevalence of congenital coronary anomalies and overall risk of sudden cardiac death in this population are not well known. Surgical intervention remains the mainstay of therapy in certain patients though recent investigations into the pathophysiology of these abnormalities have shown that the risk of surgery may outweigh the minimal reduction in risk of sudden cardiac death. |
| format | Article |
| id | doaj-art-0ffe1c5a276b4b1a8a2af1a99689eb40 |
| institution | OA Journals |
| issn | 2090-6986 2090-6994 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Vascular Medicine |
| spelling | doaj-art-0ffe1c5a276b4b1a8a2af1a99689eb402025-08-20T02:02:32ZengWileyCase Reports in Vascular Medicine2090-69862090-69942013-01-01201310.1155/2013/380952380952Anomalous Left Main Coronary Artery: Case Series of Different Courses and Literature ReviewAdam T. Marler0Jamil A. Malik1Ahmad M. Slim2Cardiology Service, San Antonio Military Medical Center, Fort Sam Houston, TX 78234, USACardiology Service, San Antonio Military Medical Center, Fort Sam Houston, TX 78234, USACardiology Service, San Antonio Military Medical Center, Fort Sam Houston, TX 78234, USABackground. Congenital anomalies of the coronary arteries are a cause of sudden cardiac death. Of the known anatomic variants, anomalous origination of a coronary artery from an opposite sinus of Valsalva (ACAOS) remains the main focus of debate. Case Series. We present three cases, all presenting to our facility within one week’s time, of patients with newly discovered anomalous origination of the left coronary artery from the right sinus of Valsalva (L-ACAOS). All patients underwent cardiac computed tomography for evaluation of coronary anatomy along with other forms of functional testing. Despite the high risk nature of two of the anomalies, the patients are being treated medically without recurrence of symptoms. Summary. After review of the literature, we have found that the risk of sudden cardiac death in patients with congenital coronary anomalies, even among variants considered the highest risk, may be overestimated. In addition, the exact prevalence of coronary anomalies in the general population is currently underestimated. A national coronary artery anomaly registry based on cardiac computed tomography and invasive coronary angiography data would be helpful in advancing our understanding of these cardiac peculiarities. The true prevalence of congenital coronary anomalies and overall risk of sudden cardiac death in this population are not well known. Surgical intervention remains the mainstay of therapy in certain patients though recent investigations into the pathophysiology of these abnormalities have shown that the risk of surgery may outweigh the minimal reduction in risk of sudden cardiac death.http://dx.doi.org/10.1155/2013/380952 |
| spellingShingle | Adam T. Marler Jamil A. Malik Ahmad M. Slim Anomalous Left Main Coronary Artery: Case Series of Different Courses and Literature Review Case Reports in Vascular Medicine |
| title | Anomalous Left Main Coronary Artery: Case Series of Different Courses and Literature Review |
| title_full | Anomalous Left Main Coronary Artery: Case Series of Different Courses and Literature Review |
| title_fullStr | Anomalous Left Main Coronary Artery: Case Series of Different Courses and Literature Review |
| title_full_unstemmed | Anomalous Left Main Coronary Artery: Case Series of Different Courses and Literature Review |
| title_short | Anomalous Left Main Coronary Artery: Case Series of Different Courses and Literature Review |
| title_sort | anomalous left main coronary artery case series of different courses and literature review |
| url | http://dx.doi.org/10.1155/2013/380952 |
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