1.25(OH)2D3 decreases PCNA and mTOR expression and alleviates renal injury in Thy-1 nephritis rat model.

1.25(OH)2D3 decreases PCNA and mTOR expression and alleviates renal injury in Thy-1 nephritis rat model.

<h4>Objective</h4>This study investigated the role and mechanisms of 1.25(OH)2D3 in proliferative glomerulonephritis and its effect on the regulation of mesangial cells.<h4>Methods</h4>Sixty male SD rats were randomly divided into four groups: control (CG), nephritis (NG), ne...

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Bibliographic Details
Main Authors: Jian-Feng Li, Lei Jin, Huan Ma, Jie Suo, Rui Yang, Xiao-Ping Yang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2024-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0311000
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