Phenotypic and Molecular Characterization of MCF10DCIS and SUM Breast Cancer Cell Lines
We reviewed the phenotypic and molecular characteristics of MCF10DCIS.com and the SUM cell lines based on numerous studies performed over the years. The major signaling pathways that give rise to the phenotype of these cells may serve as a good resource of information when researchers in drug discov...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2013-01-01
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| Series: | International Journal of Breast Cancer |
| Online Access: | http://dx.doi.org/10.1155/2013/872743 |
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| _version_ | 1849308390491160576 |
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| author | Nandita Barnabas Dalia Cohen |
| author_facet | Nandita Barnabas Dalia Cohen |
| author_sort | Nandita Barnabas |
| collection | DOAJ |
| description | We reviewed the phenotypic and molecular characteristics of MCF10DCIS.com and the SUM cell lines based on numerous studies performed over the years. The major signaling pathways that give rise to the phenotype of these cells may serve as a good resource of information when researchers in drug discovery and development use these cells to identify novel targets and biomarkers. Major signaling pathways and mutations affecting the coding sequence are also described providing important information when using these cells as a model in a variety of studies. |
| format | Article |
| id | doaj-art-0ff799046ed84547b23dbcd3ff3b5a22 |
| institution | Kabale University |
| issn | 2090-3170 2090-3189 |
| language | English |
| publishDate | 2013-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Breast Cancer |
| spelling | doaj-art-0ff799046ed84547b23dbcd3ff3b5a222025-08-20T03:54:29ZengWileyInternational Journal of Breast Cancer2090-31702090-31892013-01-01201310.1155/2013/872743872743Phenotypic and Molecular Characterization of MCF10DCIS and SUM Breast Cancer Cell LinesNandita Barnabas0Dalia Cohen1Asterand US, 440 Burroughs, Tech One Building, Suite 501, Detroit, MI 48202-3420, USAAsterand US, 440 Burroughs, Tech One Building, Suite 501, Detroit, MI 48202-3420, USAWe reviewed the phenotypic and molecular characteristics of MCF10DCIS.com and the SUM cell lines based on numerous studies performed over the years. The major signaling pathways that give rise to the phenotype of these cells may serve as a good resource of information when researchers in drug discovery and development use these cells to identify novel targets and biomarkers. Major signaling pathways and mutations affecting the coding sequence are also described providing important information when using these cells as a model in a variety of studies.http://dx.doi.org/10.1155/2013/872743 |
| spellingShingle | Nandita Barnabas Dalia Cohen Phenotypic and Molecular Characterization of MCF10DCIS and SUM Breast Cancer Cell Lines International Journal of Breast Cancer |
| title | Phenotypic and Molecular Characterization of MCF10DCIS and SUM Breast Cancer Cell Lines |
| title_full | Phenotypic and Molecular Characterization of MCF10DCIS and SUM Breast Cancer Cell Lines |
| title_fullStr | Phenotypic and Molecular Characterization of MCF10DCIS and SUM Breast Cancer Cell Lines |
| title_full_unstemmed | Phenotypic and Molecular Characterization of MCF10DCIS and SUM Breast Cancer Cell Lines |
| title_short | Phenotypic and Molecular Characterization of MCF10DCIS and SUM Breast Cancer Cell Lines |
| title_sort | phenotypic and molecular characterization of mcf10dcis and sum breast cancer cell lines |
| url | http://dx.doi.org/10.1155/2013/872743 |
| work_keys_str_mv | AT nanditabarnabas phenotypicandmolecularcharacterizationofmcf10dcisandsumbreastcancercelllines AT daliacohen phenotypicandmolecularcharacterizationofmcf10dcisandsumbreastcancercelllines |