An Interesting Case of Gelatinous Transformation of the Bone Marrow in a Neonate Presenting with Severe Anemia
Gelatinous transformation of the bone marrow (GTM) is a rare but reversible marrow pathology marked by fat atrophy, hematopoietic cell loss, and mucopolysaccharide deposition. We present a neonatal case with persistent anemia with Hemolytic Disease of Newborn. Bone marrow revealed PAS and Alcian Blu...
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| Format: | Article |
| Language: | English |
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Light House Polyclinic Mangalore
2025-07-01
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| Series: | Online Journal of Health & Allied Sciences |
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| Online Access: | https://www.ojhas.org/issue94/2025-2-5.html |
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| author | Shivali Sehgal Apoorva Prakash Lalita Jyotsna P Shailaja Shukla |
| author_facet | Shivali Sehgal Apoorva Prakash Lalita Jyotsna P Shailaja Shukla |
| author_sort | Shivali Sehgal |
| collection | DOAJ |
| description | Gelatinous transformation of the bone marrow (GTM) is a rare but reversible marrow pathology marked by fat atrophy, hematopoietic cell loss, and mucopolysaccharide deposition. We present a neonatal case with persistent anemia with Hemolytic Disease of Newborn. Bone marrow revealed PAS and Alcian Blue-positive gelatinous material. GTM, though non-specific, indicates severe systemic stress and must be distinguished from marrow necrosis, edema, and amyloidosis. |
| format | Article |
| id | doaj-art-0ff537b5e9724b5fb701f9850866954f |
| institution | Kabale University |
| issn | 0972-5997 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Light House Polyclinic Mangalore |
| record_format | Article |
| series | Online Journal of Health & Allied Sciences |
| spelling | doaj-art-0ff537b5e9724b5fb701f9850866954f2025-08-20T03:40:00ZengLight House Polyclinic MangaloreOnline Journal of Health & Allied Sciences0972-59972025-07-01242An Interesting Case of Gelatinous Transformation of the Bone Marrow in a Neonate Presenting with Severe AnemiaShivali Sehgal0Apoorva Prakash1Lalita Jyotsna P2Shailaja Shukla3Assistant Professor, Department of Pathology, Lady Hardinge Medical College, New Delhi, India.Postgraduate Student, Department of Pathology, Lady Hardinge Medical College, New Delhi, India.Professor, Department of Pathology, Lady Hardinge Medical College, New Delhi, India.Director Professor, Department of Pathology, Lady Hardinge Medical College, New Delhi, India.Gelatinous transformation of the bone marrow (GTM) is a rare but reversible marrow pathology marked by fat atrophy, hematopoietic cell loss, and mucopolysaccharide deposition. We present a neonatal case with persistent anemia with Hemolytic Disease of Newborn. Bone marrow revealed PAS and Alcian Blue-positive gelatinous material. GTM, though non-specific, indicates severe systemic stress and must be distinguished from marrow necrosis, edema, and amyloidosis.https://www.ojhas.org/issue94/2025-2-5.htmlgelatinous transformation of bone marrowneonateanemia |
| spellingShingle | Shivali Sehgal Apoorva Prakash Lalita Jyotsna P Shailaja Shukla An Interesting Case of Gelatinous Transformation of the Bone Marrow in a Neonate Presenting with Severe Anemia Online Journal of Health & Allied Sciences gelatinous transformation of bone marrow neonate anemia |
| title | An Interesting Case of Gelatinous Transformation of the Bone Marrow in a Neonate Presenting with Severe Anemia |
| title_full | An Interesting Case of Gelatinous Transformation of the Bone Marrow in a Neonate Presenting with Severe Anemia |
| title_fullStr | An Interesting Case of Gelatinous Transformation of the Bone Marrow in a Neonate Presenting with Severe Anemia |
| title_full_unstemmed | An Interesting Case of Gelatinous Transformation of the Bone Marrow in a Neonate Presenting with Severe Anemia |
| title_short | An Interesting Case of Gelatinous Transformation of the Bone Marrow in a Neonate Presenting with Severe Anemia |
| title_sort | interesting case of gelatinous transformation of the bone marrow in a neonate presenting with severe anemia |
| topic | gelatinous transformation of bone marrow neonate anemia |
| url | https://www.ojhas.org/issue94/2025-2-5.html |
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