Carriage of Neisseria Species in Communities with Different Rates of Meningococcal Disease
A single clone, Neisseria meningitidis serogroup C (C:2a:P1.2), was isolated from seven patients during a cluster of cases of meningococcal disease in Ontario in 1989. To determine whether the clone was present in asymptomatic individuals in the same population, pharyngeal swabs were taken from 7% (...
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| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
1992-01-01
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| Series: | Canadian Journal of Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/1992/928727 |
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| _version_ | 1832562998687825920 |
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| author | Nicole Le Saux Fraser Ashton Maksudar Rahman Alan Ryan Edward Ellis Susan Tamblyn Joan Morris Al Borczyk Caroll Mallory Donald Mikel Stephen Thompson Lyall Black Barbara Lacey Chandar Anand |
| author_facet | Nicole Le Saux Fraser Ashton Maksudar Rahman Alan Ryan Edward Ellis Susan Tamblyn Joan Morris Al Borczyk Caroll Mallory Donald Mikel Stephen Thompson Lyall Black Barbara Lacey Chandar Anand |
| author_sort | Nicole Le Saux |
| collection | DOAJ |
| description | A single clone, Neisseria meningitidis serogroup C (C:2a:P1.2), was isolated from seven patients during a cluster of cases of meningococcal disease in Ontario in 1989. To determine whether the clone was present in asymptomatic individuals in the same population, pharyngeal swabs were taken from 7% (644 of 9125) of residents who were vaccinated during the outbreak. Rates of isolation of Neisseria species were also compared to those in two other geographical areas which did not have an elevated incidence of meningococcal disease. The rate of carriage of N meningitidis in the asymptomatic individuals sampled was between 1.9% and 5.4%. The clone isolated from patients was not present among the carrier strains as determined by sero- and subtyping and electrophoretic analysis of metabolic enzymes. Age greater than six years was the only factor associated with colonization with N meningitidis. |
| format | Article |
| id | doaj-art-0fe13d70e9324d95b818c669cf105bd6 |
| institution | Kabale University |
| issn | 1180-2332 |
| language | English |
| publishDate | 1992-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Infectious Diseases |
| spelling | doaj-art-0fe13d70e9324d95b818c669cf105bd62025-02-03T01:21:16ZengWileyCanadian Journal of Infectious Diseases1180-23321992-01-0132606410.1155/1992/928727Carriage of Neisseria Species in Communities with Different Rates of Meningococcal DiseaseNicole Le Saux0Fraser Ashton1Maksudar Rahman2Alan Ryan3Edward Ellis4Susan Tamblyn5Joan Morris6Al Borczyk7Caroll Mallory8Donald Mikel9Stephen Thompson10Lyall Black11Barbara Lacey12Chandar Anand13Laboratory Centre for Disease Control (LCDC), Ottawa, Ontario, CanadaLaboratory Centre for Disease Control (LCDC), Ottawa, Ontario, CanadaReference Bacteriology Laboratories, Central Public Health Laboratory, Toronto, Ontario, CanadaLaboratory Centre for Disease Control (LCDC), Ottawa, Ontario, CanadaLaboratory Centre for Disease Control (LCDC), Ottawa, Ontario, CanadaLaboratory Centre for Disease Control (LCDC), Ottawa, Ontario, CanadaRegional Public Health Laboratory, Palmerston, Ontario, CanadaRegional Public Health Laboratory, Peterborough, Ontario, CanadaHaliburton-Kawartha-Pine Ridge Health Unit, Lindsay, Ontario, CanadaBarons-Eureka-Warner and Chinook Health Units, Coaldale, Alberta, CanadaRegional Public Health Laboratory, Peterborough, Ontario, CanadaCity of Lethbridge Health Unit, Lethbridge, Alberta, CanadaCity of Lethbridge Health Unit, Lethbridge, Alberta, CanadaAlberta Provincial Laboratory, Calgary, Alberta, CanadaA single clone, Neisseria meningitidis serogroup C (C:2a:P1.2), was isolated from seven patients during a cluster of cases of meningococcal disease in Ontario in 1989. To determine whether the clone was present in asymptomatic individuals in the same population, pharyngeal swabs were taken from 7% (644 of 9125) of residents who were vaccinated during the outbreak. Rates of isolation of Neisseria species were also compared to those in two other geographical areas which did not have an elevated incidence of meningococcal disease. The rate of carriage of N meningitidis in the asymptomatic individuals sampled was between 1.9% and 5.4%. The clone isolated from patients was not present among the carrier strains as determined by sero- and subtyping and electrophoretic analysis of metabolic enzymes. Age greater than six years was the only factor associated with colonization with N meningitidis.http://dx.doi.org/10.1155/1992/928727 |
| spellingShingle | Nicole Le Saux Fraser Ashton Maksudar Rahman Alan Ryan Edward Ellis Susan Tamblyn Joan Morris Al Borczyk Caroll Mallory Donald Mikel Stephen Thompson Lyall Black Barbara Lacey Chandar Anand Carriage of Neisseria Species in Communities with Different Rates of Meningococcal Disease Canadian Journal of Infectious Diseases |
| title | Carriage of Neisseria Species in Communities with Different Rates of Meningococcal Disease |
| title_full | Carriage of Neisseria Species in Communities with Different Rates of Meningococcal Disease |
| title_fullStr | Carriage of Neisseria Species in Communities with Different Rates of Meningococcal Disease |
| title_full_unstemmed | Carriage of Neisseria Species in Communities with Different Rates of Meningococcal Disease |
| title_short | Carriage of Neisseria Species in Communities with Different Rates of Meningococcal Disease |
| title_sort | carriage of neisseria species in communities with different rates of meningococcal disease |
| url | http://dx.doi.org/10.1155/1992/928727 |
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