Metabolomic traits of Amomum villosum Lour. fruits from different areas in Asia

Abstract Amomum villosum Lour. is an essential plant for both consumption and healing purposes. Among all the regions in China where A. villosum is grown, Yangchun City is widely regarded as the most ideal habitat for this plant. However, there were rare studies that explored the differential metabo...

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Main Authors: Zhihang Duan, Changlian Gan, Jianjun Yue, Pengfei Shen, Dongxiu Ning, Yegao Chen, Xiaohua Li
Format: Article
Language:English
Published: SpringerOpen 2025-04-01
Series:Journal of Analytical Science and Technology
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Online Access:https://doi.org/10.1186/s40543-025-00486-0
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author Zhihang Duan
Changlian Gan
Jianjun Yue
Pengfei Shen
Dongxiu Ning
Yegao Chen
Xiaohua Li
author_facet Zhihang Duan
Changlian Gan
Jianjun Yue
Pengfei Shen
Dongxiu Ning
Yegao Chen
Xiaohua Li
author_sort Zhihang Duan
collection DOAJ
description Abstract Amomum villosum Lour. is an essential plant for both consumption and healing purposes. Among all the regions in China where A. villosum is grown, Yangchun City is widely regarded as the most ideal habitat for this plant. However, there were rare studies that explored the differential metabolites between Yangchun and other regions of A. villosum fruits. The current study analyzed the metabolic profiles of A. villosum fruit samples cultivated in four representative producing areas. As a result, 260 differentially accumulated metabolites were identified in the GDYC-F versus LW-F. A total of 224 differentially accumulated metabolites were identified in the GDYC-F versus MD-F. A total of 285 differentially accumulated metabolites were identified in the YNML-F versus LW-F. A total of 262 differentially accumulated metabolites were identified in the YNML-F versus MD-F. Moreover, we identified the biomarkers to distinguish samples from different regions, including 9,12,13-TriHOME, 2-Ketobutyric acid, alpha-linolenic acid, nobiletin, sodium deoxycholate, gluconolactone and adipic acid, mifepristone, Qing Hau Sau and p-Coumaroylquinic acid, coumarin, ciliatine, methyl benzoate, 1,3-Benzenediol, (2′E,4′Z,8E)-Colneleic acid and beta-D-Fructose 6-phosphate, phenylethylamine, 4-Nitrophenol and geranyl acetate. KEGG enrichment analysis revealed that ‘Linoleic acid metabolism’ and ‘Phenylpropanoid biosynthesis’ were significant metabolic pathways among the different comparisons. The research uncovered metabolic variances in A. villosum fruits between authentic (Yangchun) and non-authentic regions across various nations, providing a scientific foundation for evaluating habitat appropriateness and introducing superior A. villosum. Subsequent research ought to confirm this study’s findings by employing more sampling sites and gathering A. villosum fruits across successive years.
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spelling doaj-art-0fdd53e7f0f24bb98330c2c4ff585a822025-08-20T02:15:15ZengSpringerOpenJournal of Analytical Science and Technology2093-33712025-04-0116111510.1186/s40543-025-00486-0Metabolomic traits of Amomum villosum Lour. fruits from different areas in AsiaZhihang Duan0Changlian Gan1Jianjun Yue2Pengfei Shen3Dongxiu Ning4Yegao Chen5Xiaohua Li6School of Traditional Dai Medicine, West Yunnan University of Apllied ScienceSchool of Traditional Dai Medicine, West Yunnan University of Apllied ScienceSchool of Traditional Dai Medicine, West Yunnan University of Apllied ScienceSchool of Traditional Dai Medicine, West Yunnan University of Apllied ScienceMengLa Hospital of Traditional Chinese Medicine and Dai MedicineSchool of Chemistry and Chemical Engineering, Yunnan Normal UniversitySchool of Traditional Dai Medicine, West Yunnan University of Apllied ScienceAbstract Amomum villosum Lour. is an essential plant for both consumption and healing purposes. Among all the regions in China where A. villosum is grown, Yangchun City is widely regarded as the most ideal habitat for this plant. However, there were rare studies that explored the differential metabolites between Yangchun and other regions of A. villosum fruits. The current study analyzed the metabolic profiles of A. villosum fruit samples cultivated in four representative producing areas. As a result, 260 differentially accumulated metabolites were identified in the GDYC-F versus LW-F. A total of 224 differentially accumulated metabolites were identified in the GDYC-F versus MD-F. A total of 285 differentially accumulated metabolites were identified in the YNML-F versus LW-F. A total of 262 differentially accumulated metabolites were identified in the YNML-F versus MD-F. Moreover, we identified the biomarkers to distinguish samples from different regions, including 9,12,13-TriHOME, 2-Ketobutyric acid, alpha-linolenic acid, nobiletin, sodium deoxycholate, gluconolactone and adipic acid, mifepristone, Qing Hau Sau and p-Coumaroylquinic acid, coumarin, ciliatine, methyl benzoate, 1,3-Benzenediol, (2′E,4′Z,8E)-Colneleic acid and beta-D-Fructose 6-phosphate, phenylethylamine, 4-Nitrophenol and geranyl acetate. KEGG enrichment analysis revealed that ‘Linoleic acid metabolism’ and ‘Phenylpropanoid biosynthesis’ were significant metabolic pathways among the different comparisons. The research uncovered metabolic variances in A. villosum fruits between authentic (Yangchun) and non-authentic regions across various nations, providing a scientific foundation for evaluating habitat appropriateness and introducing superior A. villosum. Subsequent research ought to confirm this study’s findings by employing more sampling sites and gathering A. villosum fruits across successive years.https://doi.org/10.1186/s40543-025-00486-0Amomum villosum Lour. metabonomicsGeo-authentic areaLC–MS
spellingShingle Zhihang Duan
Changlian Gan
Jianjun Yue
Pengfei Shen
Dongxiu Ning
Yegao Chen
Xiaohua Li
Metabolomic traits of Amomum villosum Lour. fruits from different areas in Asia
Journal of Analytical Science and Technology
Amomum villosum Lour. metabonomics
Geo-authentic area
LC–MS
title Metabolomic traits of Amomum villosum Lour. fruits from different areas in Asia
title_full Metabolomic traits of Amomum villosum Lour. fruits from different areas in Asia
title_fullStr Metabolomic traits of Amomum villosum Lour. fruits from different areas in Asia
title_full_unstemmed Metabolomic traits of Amomum villosum Lour. fruits from different areas in Asia
title_short Metabolomic traits of Amomum villosum Lour. fruits from different areas in Asia
title_sort metabolomic traits of amomum villosum lour fruits from different areas in asia
topic Amomum villosum Lour. metabonomics
Geo-authentic area
LC–MS
url https://doi.org/10.1186/s40543-025-00486-0
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