Intrathecal baclofen therapy in patients with spastic paraplegia: retrospective evaluation of pretreatment drugs, test dosage, dose increments and final therapy

Intrathecal baclofen therapy in patients with spastic paraplegia: retrospective evaluation of pretreatment drugs, test dosage, dose increments and final therapy

Introduction: Intrathecal baclofen therapy (ITB) is an effective alternative for severe generalized spasticity after unsuccessful oral spasmolytic therapy. Research question: What degree of severity, type and duration of pretreatment indicated ITB? What are safe test, starting and effective treatmen...

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Bibliographic Details
Main Authors: Stephan Kurz, Linda Maria Marth, Christoph-Heinrich Hoffmann, Jonas Hermann Maria Kummerant, Frederik Wilhelm Schneckmann
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Brain and Spine
Subjects:
Intrathecal baclofen therapy
Spastic paraplegia
Spasticity
Online Access:http://www.sciencedirect.com/science/article/pii/S2772529425001420
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