Mechanism of action for Troxerutin targeting the sialylation-related gene EGLN3 for the treatment of LUAD

Mechanism of action for Troxerutin targeting the sialylation-related gene EGLN3 for the treatment of LUAD

Abstract Studies have demonstrated that sialylation changes play a vital part in lung adenocarcinoma (LUAD), yet the specific mechanism is uncertain. Hence, in the present research, we screened sialylation-related biomarkers in LUAD using the bioinformatic strategy, predicted the drugs and performed...

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Bibliographic Details
Main Authors: Yanan Wu, Yanlei Ge, Junqing Gan, Ye Jin, Yishuang Cui, Xuan Zheng, Xuemin Yao, Guogui Sun
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
Lung adenocarcinoma
Sialylation
Troxerutin
EGLN3
Online Access:https://doi.org/10.1038/s41598-025-92028-2
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