Clinicoepidemiological Study of Cutaneous Leishmaniasis: A Hospital Based Study

Introduction: Cutaneous leishmaniasis is a tropical disease transmitted by the bite of an intracellular parasite infected sandfly. Visceral leishmaniasis is common in Nepal. However, cutaneous leishmaniasis remains rare with only limited number of cases documented in Nepal. Objectives: To describ...

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Main Authors: Sushmita Pradhan, Shristee Shrestha, Damber Khadka, Niraj Parajuli, Suwash Baral, Daisuke Tsuruta
Format: Article
Language:English
Published: Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON) 2023-03-01
Series:Nepal Journal of Dermatology, Venereology & Leprology
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Online Access:https://nepjol.info/index.php/NJDVL/article/view/49262
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author Sushmita Pradhan
Shristee Shrestha
Damber Khadka
Niraj Parajuli
Suwash Baral
Daisuke Tsuruta
author_facet Sushmita Pradhan
Shristee Shrestha
Damber Khadka
Niraj Parajuli
Suwash Baral
Daisuke Tsuruta
author_sort Sushmita Pradhan
collection DOAJ
description Introduction: Cutaneous leishmaniasis is a tropical disease transmitted by the bite of an intracellular parasite infected sandfly. Visceral leishmaniasis is common in Nepal. However, cutaneous leishmaniasis remains rare with only limited number of cases documented in Nepal. Objectives: To describe the clinical and epidemiological distribution of cutaneous leishmaniasis in Karnali province of Nepal. Materials and Methods: All cases clinically diagnosed from direct microscopic Giemsa-stain smears, histopathology or fine needle aspiration cytology as cutaneous leishmaniasis were enrolled in the study for one year. Demographic data and clinical details were recorded on a printed proforma. Statistical analysis was done using STATA/SE version 15.0 for MacBook. Results: Only 46 cases with age ranging from 2 to 75 years were included in the study. Mean age was 23±2.45 years. Majority of cases below 20 years (47.83%) were infected. Male to female ratio was 0.70:1. Mean duration of the disease was 4.96±0.47 months. Single lesions (73.91%) were mostly present. Single lesions were particularly presented on the face (73.53%). Cutaneous leishmaniasis (95.65%) outnumbered mucocutaneous one on lips (4.35%). Ulcerative-papulonodular type lesions (58.70%) were mostly presented in the cases. Kalikot district (56.52%) had the majority of cutaneous leishmaniasis cases in Karnali province. Majority of the cases presented during the months of February, March, April, August, November, and December (65.22%). Conclusion: The study concluded that the increase in cutaneous leishmaniasis is alarming in the Kalikot district of Karnali province in Nepal. The result of this study would continue contributing to the existing data in the literature and encourage early diagnosis and treatment of cutaneous leishmaniasis.
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institution Kabale University
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language English
publishDate 2023-03-01
publisher Society of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON)
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spelling doaj-art-0fce8034d6284a89ad581d0ef493e8602025-08-24T10:05:43ZengSociety of Dermatologists, Venereologists and Leprologists of Nepal (SODVELON)Nepal Journal of Dermatology, Venereology & Leprology2091-02312091-167X2023-03-01211Clinicoepidemiological Study of Cutaneous Leishmaniasis: A Hospital Based StudySushmita Pradhan0https://orcid.org/0000-0002-7569-4719Shristee Shrestha1Damber Khadka2Niraj Parajuli3https://orcid.org/0000-0001-6869-4959Suwash Baral4Daisuke Tsuruta5https://orcid.org/0000-0001-6283-0251Province Hospital, Karnali Province, Birendranagar, Surkhet, NepalProvince Hospital, Karnali Province, Birendranagar, Surkhet, NepalProvince Hospital, Karnali Province, Birendranagar, Surkhet, NepalNational Academy of Medical Sciences, Bir Hospital, Kathmandu, NepalAnandaban Hospital, The Leprosy Mission Nepal, Tikabhairab, Lele, Lalitpur, Nepal Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan Introduction: Cutaneous leishmaniasis is a tropical disease transmitted by the bite of an intracellular parasite infected sandfly. Visceral leishmaniasis is common in Nepal. However, cutaneous leishmaniasis remains rare with only limited number of cases documented in Nepal. Objectives: To describe the clinical and epidemiological distribution of cutaneous leishmaniasis in Karnali province of Nepal. Materials and Methods: All cases clinically diagnosed from direct microscopic Giemsa-stain smears, histopathology or fine needle aspiration cytology as cutaneous leishmaniasis were enrolled in the study for one year. Demographic data and clinical details were recorded on a printed proforma. Statistical analysis was done using STATA/SE version 15.0 for MacBook. Results: Only 46 cases with age ranging from 2 to 75 years were included in the study. Mean age was 23±2.45 years. Majority of cases below 20 years (47.83%) were infected. Male to female ratio was 0.70:1. Mean duration of the disease was 4.96±0.47 months. Single lesions (73.91%) were mostly present. Single lesions were particularly presented on the face (73.53%). Cutaneous leishmaniasis (95.65%) outnumbered mucocutaneous one on lips (4.35%). Ulcerative-papulonodular type lesions (58.70%) were mostly presented in the cases. Kalikot district (56.52%) had the majority of cutaneous leishmaniasis cases in Karnali province. Majority of the cases presented during the months of February, March, April, August, November, and December (65.22%). Conclusion: The study concluded that the increase in cutaneous leishmaniasis is alarming in the Kalikot district of Karnali province in Nepal. The result of this study would continue contributing to the existing data in the literature and encourage early diagnosis and treatment of cutaneous leishmaniasis. https://nepjol.info/index.php/NJDVL/article/view/49262Cutaneous leishmaniasisDiagnosisFine-needle aspiration cytologyGiemsa-stain smearsHistopathologyNepal
spellingShingle Sushmita Pradhan
Shristee Shrestha
Damber Khadka
Niraj Parajuli
Suwash Baral
Daisuke Tsuruta
Clinicoepidemiological Study of Cutaneous Leishmaniasis: A Hospital Based Study
Nepal Journal of Dermatology, Venereology & Leprology
Cutaneous leishmaniasis
Diagnosis
Fine-needle aspiration cytology
Giemsa-stain smears
Histopathology
Nepal
title Clinicoepidemiological Study of Cutaneous Leishmaniasis: A Hospital Based Study
title_full Clinicoepidemiological Study of Cutaneous Leishmaniasis: A Hospital Based Study
title_fullStr Clinicoepidemiological Study of Cutaneous Leishmaniasis: A Hospital Based Study
title_full_unstemmed Clinicoepidemiological Study of Cutaneous Leishmaniasis: A Hospital Based Study
title_short Clinicoepidemiological Study of Cutaneous Leishmaniasis: A Hospital Based Study
title_sort clinicoepidemiological study of cutaneous leishmaniasis a hospital based study
topic Cutaneous leishmaniasis
Diagnosis
Fine-needle aspiration cytology
Giemsa-stain smears
Histopathology
Nepal
url https://nepjol.info/index.php/NJDVL/article/view/49262
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