Current Status of Norovirus Infections in Children in Sub-Saharan Africa
Noroviruses are a leading cause of acute sporadic gastroenteritis worldwide. In Sub-Saharan Africa, information regarding norovirus infections in children is scarce. A systematic review of studies performed between 1993 and June 2015 was conducted to establish the genotypic distribution and prevalen...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Journal of Tropical Medicine |
| Online Access: | http://dx.doi.org/10.1155/2015/309648 |
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| author | Samuel Munalula Munjita |
| author_facet | Samuel Munalula Munjita |
| author_sort | Samuel Munalula Munjita |
| collection | DOAJ |
| description | Noroviruses are a leading cause of acute sporadic gastroenteritis worldwide. In Sub-Saharan Africa, information regarding norovirus infections in children is scarce. A systematic review of studies performed between 1993 and June 2015 was conducted to establish the genotypic distribution and prevalence of norovirus infections in children (≤17) in Sub-Saharan Africa. Analysis of data from 19 studies involving 8,399 samples from children with symptomatic and nonsymptomatic gastroenteritis revealed prevalence of 12.6% (range 4.6% to 32.4%). The prevalence of norovirus infections was higher in symptomatic children (14.2%) than asymptomatic children (9.2%). Genogroup II (GII) was the most prevalent genogroup accounting for 76.4% of all the reported norovirus infections. The rest of the infections were GI (21.7%) and GI/GII (1.9%). The most common genotypes were GII.4 (65.2%), GI.7 (33.3%), and GI.3 (21.3%). These statistics were calculated from studies carried out in 12 out of 48 Sub-Saharan African countries. Therefore, more studies involving several countries are required to determine fully the epidemiology of noroviruses and their contribution to childhood diarrhoea in Sub-Saharan Africa. |
| format | Article |
| id | doaj-art-0fcac371268d46ddb06a625304cfac7b |
| institution | Kabale University |
| issn | 1687-9686 1687-9694 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Tropical Medicine |
| spelling | doaj-art-0fcac371268d46ddb06a625304cfac7b2025-02-03T05:54:40ZengWileyJournal of Tropical Medicine1687-96861687-96942015-01-01201510.1155/2015/309648309648Current Status of Norovirus Infections in Children in Sub-Saharan AfricaSamuel Munalula Munjita0Department of Biomedical Sciences, School of Medicine, University of Zambia, 15101 Lusaka, ZambiaNoroviruses are a leading cause of acute sporadic gastroenteritis worldwide. In Sub-Saharan Africa, information regarding norovirus infections in children is scarce. A systematic review of studies performed between 1993 and June 2015 was conducted to establish the genotypic distribution and prevalence of norovirus infections in children (≤17) in Sub-Saharan Africa. Analysis of data from 19 studies involving 8,399 samples from children with symptomatic and nonsymptomatic gastroenteritis revealed prevalence of 12.6% (range 4.6% to 32.4%). The prevalence of norovirus infections was higher in symptomatic children (14.2%) than asymptomatic children (9.2%). Genogroup II (GII) was the most prevalent genogroup accounting for 76.4% of all the reported norovirus infections. The rest of the infections were GI (21.7%) and GI/GII (1.9%). The most common genotypes were GII.4 (65.2%), GI.7 (33.3%), and GI.3 (21.3%). These statistics were calculated from studies carried out in 12 out of 48 Sub-Saharan African countries. Therefore, more studies involving several countries are required to determine fully the epidemiology of noroviruses and their contribution to childhood diarrhoea in Sub-Saharan Africa.http://dx.doi.org/10.1155/2015/309648 |
| spellingShingle | Samuel Munalula Munjita Current Status of Norovirus Infections in Children in Sub-Saharan Africa Journal of Tropical Medicine |
| title | Current Status of Norovirus Infections in Children in Sub-Saharan Africa |
| title_full | Current Status of Norovirus Infections in Children in Sub-Saharan Africa |
| title_fullStr | Current Status of Norovirus Infections in Children in Sub-Saharan Africa |
| title_full_unstemmed | Current Status of Norovirus Infections in Children in Sub-Saharan Africa |
| title_short | Current Status of Norovirus Infections in Children in Sub-Saharan Africa |
| title_sort | current status of norovirus infections in children in sub saharan africa |
| url | http://dx.doi.org/10.1155/2015/309648 |
| work_keys_str_mv | AT samuelmunalulamunjita currentstatusofnorovirusinfectionsinchildreninsubsaharanafrica |