DEVELOPMENT OF MICROREACTOR METHOD FOR POLYMERIC MICROSPHERES PRODUCTION USED IN TEST SYSTEMS BASED ON LATEX AGGLUTINATION REACTION
Some steps were taken to elaborate a method for the preparation of polymeric microspheres using flow microreactors by emulsifying the solution of methacrylic acid esters copolymer in an aqueous PVA solution followed by extraction and evaporation of the solvent. The effect of process parameters on th...
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| Format: | Article |
| Language: | Russian |
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MIREA - Russian Technological University
2013-08-01
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| Series: | Тонкие химические технологии |
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| Online Access: | https://www.finechem-mirea.ru/jour/article/view/564 |
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| author | S. A. Kedik E. A. Petrova E. S. Zhavoronok A. V. Panov V. V. Suslov |
| author_facet | S. A. Kedik E. A. Petrova E. S. Zhavoronok A. V. Panov V. V. Suslov |
| author_sort | S. A. Kedik |
| collection | DOAJ |
| description | Some steps were taken to elaborate a method for the preparation of polymeric microspheres using flow microreactors by emulsifying the solution of methacrylic acid esters copolymer in an aqueous PVA solution followed by extraction and evaporation of the solvent. The effect of process parameters on the characteristics of polymeric microspheres with a predetermined set of properties (mean size, polydispersity) potentially suitable for use as carriers in bioligands for diagnostic test systems was investigated. The dependence of the average particle size on the microreactor type, concentration of copolymer solution in methylene chloride and polyvinyl alcohol in water and the ratio of flow rates of organic and aqueous phases was stated, and the optimal process conditions were selected. |
| format | Article |
| id | doaj-art-0fc096d7916348339c68decda9cdc286 |
| institution | DOAJ |
| issn | 2410-6593 2686-7575 |
| language | Russian |
| publishDate | 2013-08-01 |
| publisher | MIREA - Russian Technological University |
| record_format | Article |
| series | Тонкие химические технологии |
| spelling | doaj-art-0fc096d7916348339c68decda9cdc2862025-08-20T03:00:01ZrusMIREA - Russian Technological UniversityТонкие химические технологии2410-65932686-75752013-08-01841117558DEVELOPMENT OF MICROREACTOR METHOD FOR POLYMERIC MICROSPHERES PRODUCTION USED IN TEST SYSTEMS BASED ON LATEX AGGLUTINATION REACTIONS. A. Kedik0E. A. Petrova1E. S. Zhavoronok2A. V. Panov3V. V. Suslov4M.V. Lomonosov Moscow State University of Fine Chemical Technologies, 86, Vernadskogo pr., Moscow 119571M.V. Lomonosov Moscow State University of Fine Chemical Technologies, 86, Vernadskogo pr., Moscow 119571M.V. Lomonosov Moscow State University of Fine Chemical Technologies, 86, Vernadskogo pr., Moscow 119571M.V. Lomonosov Moscow State University of Fine Chemical Technologies, 86, Vernadskogo pr., Moscow 119571M.V. Lomonosov Moscow State University of Fine Chemical Technologies, 86, Vernadskogo pr., Moscow 119571Some steps were taken to elaborate a method for the preparation of polymeric microspheres using flow microreactors by emulsifying the solution of methacrylic acid esters copolymer in an aqueous PVA solution followed by extraction and evaporation of the solvent. The effect of process parameters on the characteristics of polymeric microspheres with a predetermined set of properties (mean size, polydispersity) potentially suitable for use as carriers in bioligands for diagnostic test systems was investigated. The dependence of the average particle size on the microreactor type, concentration of copolymer solution in methylene chloride and polyvinyl alcohol in water and the ratio of flow rates of organic and aqueous phases was stated, and the optimal process conditions were selected.https://www.finechem-mirea.ru/jour/article/view/564polymeric microspheres, diagnostic test systems, flow microreactors, latex agglutination. |
| spellingShingle | S. A. Kedik E. A. Petrova E. S. Zhavoronok A. V. Panov V. V. Suslov DEVELOPMENT OF MICROREACTOR METHOD FOR POLYMERIC MICROSPHERES PRODUCTION USED IN TEST SYSTEMS BASED ON LATEX AGGLUTINATION REACTION Тонкие химические технологии polymeric microspheres, diagnostic test systems, flow microreactors, latex agglutination. |
| title | DEVELOPMENT OF MICROREACTOR METHOD FOR POLYMERIC MICROSPHERES PRODUCTION USED IN TEST SYSTEMS BASED ON LATEX AGGLUTINATION REACTION |
| title_full | DEVELOPMENT OF MICROREACTOR METHOD FOR POLYMERIC MICROSPHERES PRODUCTION USED IN TEST SYSTEMS BASED ON LATEX AGGLUTINATION REACTION |
| title_fullStr | DEVELOPMENT OF MICROREACTOR METHOD FOR POLYMERIC MICROSPHERES PRODUCTION USED IN TEST SYSTEMS BASED ON LATEX AGGLUTINATION REACTION |
| title_full_unstemmed | DEVELOPMENT OF MICROREACTOR METHOD FOR POLYMERIC MICROSPHERES PRODUCTION USED IN TEST SYSTEMS BASED ON LATEX AGGLUTINATION REACTION |
| title_short | DEVELOPMENT OF MICROREACTOR METHOD FOR POLYMERIC MICROSPHERES PRODUCTION USED IN TEST SYSTEMS BASED ON LATEX AGGLUTINATION REACTION |
| title_sort | development of microreactor method for polymeric microspheres production used in test systems based on latex agglutination reaction |
| topic | polymeric microspheres, diagnostic test systems, flow microreactors, latex agglutination. |
| url | https://www.finechem-mirea.ru/jour/article/view/564 |
| work_keys_str_mv | AT sakedik developmentofmicroreactormethodforpolymericmicrospheresproductionusedintestsystemsbasedonlatexagglutinationreaction AT eapetrova developmentofmicroreactormethodforpolymericmicrospheresproductionusedintestsystemsbasedonlatexagglutinationreaction AT eszhavoronok developmentofmicroreactormethodforpolymericmicrospheresproductionusedintestsystemsbasedonlatexagglutinationreaction AT avpanov developmentofmicroreactormethodforpolymericmicrospheresproductionusedintestsystemsbasedonlatexagglutinationreaction AT vvsuslov developmentofmicroreactormethodforpolymericmicrospheresproductionusedintestsystemsbasedonlatexagglutinationreaction |