Efficacy of perioperative esketamine on postoperative depression: a systematic review and meta-analysis

Efficacy of perioperative esketamine on postoperative depression: a systematic review and meta-analysis

BackgroundPostoperative depression (POD) represents a serious complication in surgical patients, exacerbating morbidity and mortality rates while imposing a substantial economic burden on healthcare systems. Despite its widespread clinical use, the role of esketamine, an NMDA receptor antagonist wit...

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Bibliographic Details
Main Authors:	Hao-Yan Li, Wen-Jing Xu, Ya-Mei Wang, Shuang Xie, Huan-Liang Wang
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-04-01
Series:	Frontiers in Psychiatry
Subjects:	esketamine postoperative depression anesthesia meta-analysis
Online Access:	https://www.frontiersin.org/articles/10.3389/fpsyt.2025.1476449/full
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