Analyses of Ferrous and Ferric State in DynabiTab Using Mössbauer Spectroscopy

Antianemic medicament ferrous gluconate, ferrous fumarate, and a Dynabi tablet with a basic iron bearing ingredient were studied with the use of Mössbauer spectroscopy. Room temperature spectra of ferrous gluconate gave clear evidence that the two phases of iron were present: ferrous (Fe2+) as a maj...

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Bibliographic Details
Main Authors: Young Rang Uhm, Jae Cheong Lim, Sang Mu Choi
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:International Journal of Analytical Chemistry
Online Access:http://dx.doi.org/10.1155/2017/9321896
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Summary:Antianemic medicament ferrous gluconate, ferrous fumarate, and a Dynabi tablet with a basic iron bearing ingredient were studied with the use of Mössbauer spectroscopy. Room temperature spectra of ferrous gluconate gave clear evidence that the two phases of iron were present: ferrous (Fe2+) as a major one with a contribution at and above 91 a.u.% and ferric (Fe3+) whose contribution was found to be ~9 a.u.%. In the case of ferrous fumarate, a single phase was measured corresponding to ferrous (Fe2+) state. A Dynabi tablet consists of ferrous fumarate and ferrous fumarate. The ferric phase in ferrous gluconate is able to be reached about ~3.6 a.u.% in a tablet.
ISSN:1687-8760
1687-8779