Treatment of thrice-negative breast cancer in a patient with metabolic syndrome

Breast cancer (BC) remains one of the most common diseases of the female population. According to statistics, breast cancer is detected in every eighth woman. Approximately 20‑24% of breast cancer patients are diagnosed with triple negative breast cancer. Triple‑negative breast cancer is characteriz...

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Main Authors: G. E. Roitberg, J. V. Dorosh, O. Yu. Anikeeva
Format: Article
Language:Russian
Published: QUASAR, LLC 2021-03-01
Series:Исследования и практика в медицине
Subjects:
Online Access:https://www.rpmj.ru/rpmj/article/view/674
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author G. E. Roitberg
J. V. Dorosh
O. Yu. Anikeeva
author_facet G. E. Roitberg
J. V. Dorosh
O. Yu. Anikeeva
author_sort G. E. Roitberg
collection DOAJ
description Breast cancer (BC) remains one of the most common diseases of the female population. According to statistics, breast cancer is detected in every eighth woman. Approximately 20‑24% of breast cancer patients are diagnosed with triple negative breast cancer. Triple‑negative breast cancer is characterized by an aggressive clinical course, a higher relapse rate, and low overall survival. According to statistics, the median survival rate for women with metastatic triple‑negative breast cancer is less than one year. We demonstrate a successful case of treatment of a 60‑year‑old woman diagnosed with triple negative breast cancer on the right, edematous‑infiltrative form, St IIIC cT4bN3M0 on the background of metabolic syndrome. Antitumor treatment lasted 1 year and consisted of three stages: systemic chemotherapy, surgical treatment (radical mastectomy), and adjuvant radiation therapy. After the treatment, remission was achieved. The patient is alive and has a relapse‑free period of 3 years. Conclusion. Despite the severe concomitant pathology in the observed patient, we received a positive result of multi‑ stage therapy, where cytotoxic chemotherapy was the basic treatment for a woman with triple negative breast cancer.
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institution Kabale University
issn 2410-1893
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series Исследования и практика в медицине
spelling doaj-art-0fa5ab4795b84eee9506d434c7a6fb7d2025-08-20T04:00:14ZrusQUASAR, LLCИсследования и практика в медицине2410-18932021-03-0181626810.17709/2409-2231-2021-8-1-6368Treatment of thrice-negative breast cancer in a patient with metabolic syndromeG. E. Roitberg0J. V. Dorosh1O. Yu. Anikeeva2N.I.Pirogov Russian National Research Medical University (RNRMU); “Medicinа”N.I.Pirogov Russian National Research Medical University (RNRMU)“Medicinа”Breast cancer (BC) remains one of the most common diseases of the female population. According to statistics, breast cancer is detected in every eighth woman. Approximately 20‑24% of breast cancer patients are diagnosed with triple negative breast cancer. Triple‑negative breast cancer is characterized by an aggressive clinical course, a higher relapse rate, and low overall survival. According to statistics, the median survival rate for women with metastatic triple‑negative breast cancer is less than one year. We demonstrate a successful case of treatment of a 60‑year‑old woman diagnosed with triple negative breast cancer on the right, edematous‑infiltrative form, St IIIC cT4bN3M0 on the background of metabolic syndrome. Antitumor treatment lasted 1 year and consisted of three stages: systemic chemotherapy, surgical treatment (radical mastectomy), and adjuvant radiation therapy. After the treatment, remission was achieved. The patient is alive and has a relapse‑free period of 3 years. Conclusion. Despite the severe concomitant pathology in the observed patient, we received a positive result of multi‑ stage therapy, where cytotoxic chemotherapy was the basic treatment for a woman with triple negative breast cancer.https://www.rpmj.ru/rpmj/article/view/674triple negative breast cancermetabolic syndromechemotherapyradical mastectomyadjuvant radiation therapymetabolic syndromediabetes mellitus
spellingShingle G. E. Roitberg
J. V. Dorosh
O. Yu. Anikeeva
Treatment of thrice-negative breast cancer in a patient with metabolic syndrome
Исследования и практика в медицине
triple negative breast cancer
metabolic syndrome
chemotherapy
radical mastectomy
adjuvant radiation therapy
metabolic syndrome
diabetes mellitus
title Treatment of thrice-negative breast cancer in a patient with metabolic syndrome
title_full Treatment of thrice-negative breast cancer in a patient with metabolic syndrome
title_fullStr Treatment of thrice-negative breast cancer in a patient with metabolic syndrome
title_full_unstemmed Treatment of thrice-negative breast cancer in a patient with metabolic syndrome
title_short Treatment of thrice-negative breast cancer in a patient with metabolic syndrome
title_sort treatment of thrice negative breast cancer in a patient with metabolic syndrome
topic triple negative breast cancer
metabolic syndrome
chemotherapy
radical mastectomy
adjuvant radiation therapy
metabolic syndrome
diabetes mellitus
url https://www.rpmj.ru/rpmj/article/view/674
work_keys_str_mv AT geroitberg treatmentofthricenegativebreastcancerinapatientwithmetabolicsyndrome
AT jvdorosh treatmentofthricenegativebreastcancerinapatientwithmetabolicsyndrome
AT oyuanikeeva treatmentofthricenegativebreastcancerinapatientwithmetabolicsyndrome