BRCA1 and BRCA2 as prognostic markers in oral squamous cell carcinoma: a minireview

BRCA1 and BRCA2 as prognostic markers in oral squamous cell carcinoma: a minireview

Oral squamous cell carcinoma (OSCC), a subset of head and neck cancers, primarily originates in the epithelial tissues of the oral cavity. Despite advancements in treatment, the mortality rate for OSCC remains around 50%, underscoring the urgent need for improved prognostic markers. This review expl...

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Bibliographic Details
Main Authors: Dominika Gedeonová, Claretta Bianchi, Jan Štembírek, Matouš Hrdinka, Zuzana Chyra, Marcela Buchtová, Pavel Hurník, Tomáš Blažek, Jana Režnarová
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Oncology
Subjects:
BRCA1
BRCA2
OSCC (oral squamous cell carcinoma)
HNSCC (head and neck squamous cell carcinoma)
gene alteration
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1528822/full
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