Jejunal Varices Bleeding in a Patient with Extensive Portomesenteric Thrombosis Secondary to Factor V Leiden Mutation: A Management Dilemma

Ectopic varices are portosystemic collaterals that occur away from the gastroesophageal junction and account for 1-5% of all variceal bleeding. Its occurrence in the jejunum is rare. Most common cause of ectopic jejunal varices is portal hypertension especially in those patients who have undergone p...

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Main Authors: Ahmad Ayash, Kamran Mushtaq, Mohamed Emad Abdul Qader, Khalid Mohsin Al-Ejji, Saad Rashid Al Kaabi, Shadi J. S. Khelfa
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Case Reports in Gastrointestinal Medicine
Online Access:http://dx.doi.org/10.1155/2019/4526472
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author Ahmad Ayash
Kamran Mushtaq
Mohamed Emad Abdul Qader
Khalid Mohsin Al-Ejji
Saad Rashid Al Kaabi
Shadi J. S. Khelfa
author_facet Ahmad Ayash
Kamran Mushtaq
Mohamed Emad Abdul Qader
Khalid Mohsin Al-Ejji
Saad Rashid Al Kaabi
Shadi J. S. Khelfa
author_sort Ahmad Ayash
collection DOAJ
description Ectopic varices are portosystemic collaterals that occur away from the gastroesophageal junction and account for 1-5% of all variceal bleeding. Its occurrence in the jejunum is rare. Most common cause of ectopic jejunal varices is portal hypertension especially in those patients who have undergone prior abdominal surgery. Portomesenteric thrombosis is a rare cause of ectopic jejunal varices. Ectopic varices are rare cause of obscure GI bleeding and hence should be always suspected in patients with history of portal hypertension who present with GI bleeding and have negative upper and lower GI endoscopies. Management of patients with ectopic varices is often very challenging and requires multidisciplinary approach. Therapeutic options include endoscopic therapy, interventional radiologic procedures, surgically creating shunting, or surgical resection. We present the case of a 52-year-old patient who was on anticoagulation for extensive portomesenteric thrombosis secondary to factor V Leiden heterozygous mutation and presented with melena and symptomatic anemia. Investigations showed bleeding jejunal varices as the cause of anemia. We discuss the therapeutic options and dilemma in the management of such cases.
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publishDate 2019-01-01
publisher Wiley
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series Case Reports in Gastrointestinal Medicine
spelling doaj-art-0fa05c61e6b3426ba5c2bceb816cd7f82025-08-20T02:01:40ZengWileyCase Reports in Gastrointestinal Medicine2090-65282090-65362019-01-01201910.1155/2019/45264724526472Jejunal Varices Bleeding in a Patient with Extensive Portomesenteric Thrombosis Secondary to Factor V Leiden Mutation: A Management DilemmaAhmad Ayash0Kamran Mushtaq1Mohamed Emad Abdul Qader2Khalid Mohsin Al-Ejji3Saad Rashid Al Kaabi4Shadi J. S. Khelfa5Department of Gastroenterology, Hamad Medical Corporation, Doha, QatarDepartment of Gastroenterology, Hamad Medical Corporation, Doha, QatarDepartment of Internal Medicine, Hamad Medical Corporation, Doha, QatarDepartment of Gastroenterology, Hamad Medical Corporation, Doha, QatarDepartment of Gastroenterology, Hamad Medical Corporation, Doha, QatarDepartment of Gastroenterology, Hamad Medical Corporation, Doha, QatarEctopic varices are portosystemic collaterals that occur away from the gastroesophageal junction and account for 1-5% of all variceal bleeding. Its occurrence in the jejunum is rare. Most common cause of ectopic jejunal varices is portal hypertension especially in those patients who have undergone prior abdominal surgery. Portomesenteric thrombosis is a rare cause of ectopic jejunal varices. Ectopic varices are rare cause of obscure GI bleeding and hence should be always suspected in patients with history of portal hypertension who present with GI bleeding and have negative upper and lower GI endoscopies. Management of patients with ectopic varices is often very challenging and requires multidisciplinary approach. Therapeutic options include endoscopic therapy, interventional radiologic procedures, surgically creating shunting, or surgical resection. We present the case of a 52-year-old patient who was on anticoagulation for extensive portomesenteric thrombosis secondary to factor V Leiden heterozygous mutation and presented with melena and symptomatic anemia. Investigations showed bleeding jejunal varices as the cause of anemia. We discuss the therapeutic options and dilemma in the management of such cases.http://dx.doi.org/10.1155/2019/4526472
spellingShingle Ahmad Ayash
Kamran Mushtaq
Mohamed Emad Abdul Qader
Khalid Mohsin Al-Ejji
Saad Rashid Al Kaabi
Shadi J. S. Khelfa
Jejunal Varices Bleeding in a Patient with Extensive Portomesenteric Thrombosis Secondary to Factor V Leiden Mutation: A Management Dilemma
Case Reports in Gastrointestinal Medicine
title Jejunal Varices Bleeding in a Patient with Extensive Portomesenteric Thrombosis Secondary to Factor V Leiden Mutation: A Management Dilemma
title_full Jejunal Varices Bleeding in a Patient with Extensive Portomesenteric Thrombosis Secondary to Factor V Leiden Mutation: A Management Dilemma
title_fullStr Jejunal Varices Bleeding in a Patient with Extensive Portomesenteric Thrombosis Secondary to Factor V Leiden Mutation: A Management Dilemma
title_full_unstemmed Jejunal Varices Bleeding in a Patient with Extensive Portomesenteric Thrombosis Secondary to Factor V Leiden Mutation: A Management Dilemma
title_short Jejunal Varices Bleeding in a Patient with Extensive Portomesenteric Thrombosis Secondary to Factor V Leiden Mutation: A Management Dilemma
title_sort jejunal varices bleeding in a patient with extensive portomesenteric thrombosis secondary to factor v leiden mutation a management dilemma
url http://dx.doi.org/10.1155/2019/4526472
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