In vitro evaluation of antioxidant and antimicrobial properties of Cordia mocleodii leaf extract
Cordia macleodii has long served as a medicinal plant for its hepatoprotective and wound healing properties. People utilize this plant in treating various diseases due to the presence of relatively high levels of flavonoids, alkaloids, steroids, and terpenoids. This study aimed to investigate the in...
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| Format: | Article |
| Language: | English |
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Bangladesh Society for Microbiology, Immunology, and Advanced Biotechnology
2024-04-01
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| Series: | Plant Trends |
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| Online Access: | http://www.ejmanager.com/fulltextpdf.php?mno=201035 |
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| author | Sajidur Rahman Akash Samia Alam Etha Md. Redowan Hossain Sonet Enamul Hoque Md. Sujunur Rahman Md. Nasir Uddin Ohidul Islam Dr. Lubna Jahan |
| author_facet | Sajidur Rahman Akash Samia Alam Etha Md. Redowan Hossain Sonet Enamul Hoque Md. Sujunur Rahman Md. Nasir Uddin Ohidul Islam Dr. Lubna Jahan |
| author_sort | Sajidur Rahman Akash |
| collection | DOAJ |
| description | Cordia macleodii has long served as a medicinal plant for its hepatoprotective and wound healing properties. People utilize this plant in treating various diseases due to the presence of relatively high levels of flavonoids, alkaloids, steroids, and terpenoids. This study aimed to investigate the in vitro antibacterial and antioxidant properties of Cordia macleodii methanol leaf extract. The antioxidant activity of the methanol extract of Cordia macleodii leaves was determined using the DPPH scavenging test, total phenol content (TPC), and total flavonoid content (TFC). The antibacterial activity was evaluated using the disc diffusion method. The extract exhibited significant dose-dependent antioxidant activity comparable to ascorbic acid. The total flavonoid content was 611.9 mg/g, and the total phenol content was 164.4 mg/g. The DPPH free radical scavenging assay indicated an ascorbic acid production of 523.21 μg/ml, while routine tests showed 18.35 μg/ml. Additionally, the leaf extracts demonstrated strong antibacterial activity against various bacteria, even exceeding the effectiveness of Ciprofloxacin. Further research is necessary to develop targeted therapies, potentially opening new avenues for harnessing the medicinal properties of Cordia macleodii. Clinical studies are also needed to investigate its potential as an alternative medicine. [Plant Trends 2024; 2(2.000): 38-45] |
| format | Article |
| id | doaj-art-0f9bf669feb64bb8a4acec41a7549101 |
| institution | DOAJ |
| issn | 3006-5658 |
| language | English |
| publishDate | 2024-04-01 |
| publisher | Bangladesh Society for Microbiology, Immunology, and Advanced Biotechnology |
| record_format | Article |
| series | Plant Trends |
| spelling | doaj-art-0f9bf669feb64bb8a4acec41a75491012025-08-20T02:45:49ZengBangladesh Society for Microbiology, Immunology, and Advanced BiotechnologyPlant Trends3006-56582024-04-0122384510.5455/pt.2024.04201035In vitro evaluation of antioxidant and antimicrobial properties of Cordia mocleodii leaf extractSajidur Rahman Akash0Samia Alam Etha1Md. Redowan Hossain Sonet2Enamul Hoque3Md. Sujunur Rahman4Md. Nasir Uddin5Ohidul Islam6Dr. Lubna Jahan7Bangladesh University, Dhaka, Bangladesh Bangladesh University, Dhaka, Bangladesh Bangladesh University, Dhaka, Bangladesh Bangladesh University, Dhaka, Bangladesh Bangladesh University, Dhaka, Bangladesh Bangladesh University, Dhaka, Bangladesh Bangladesh University, Dhaka, Bangladesh Bangladesh University, Dhaka, BangladeshCordia macleodii has long served as a medicinal plant for its hepatoprotective and wound healing properties. People utilize this plant in treating various diseases due to the presence of relatively high levels of flavonoids, alkaloids, steroids, and terpenoids. This study aimed to investigate the in vitro antibacterial and antioxidant properties of Cordia macleodii methanol leaf extract. The antioxidant activity of the methanol extract of Cordia macleodii leaves was determined using the DPPH scavenging test, total phenol content (TPC), and total flavonoid content (TFC). The antibacterial activity was evaluated using the disc diffusion method. The extract exhibited significant dose-dependent antioxidant activity comparable to ascorbic acid. The total flavonoid content was 611.9 mg/g, and the total phenol content was 164.4 mg/g. The DPPH free radical scavenging assay indicated an ascorbic acid production of 523.21 μg/ml, while routine tests showed 18.35 μg/ml. Additionally, the leaf extracts demonstrated strong antibacterial activity against various bacteria, even exceeding the effectiveness of Ciprofloxacin. Further research is necessary to develop targeted therapies, potentially opening new avenues for harnessing the medicinal properties of Cordia macleodii. Clinical studies are also needed to investigate its potential as an alternative medicine. [Plant Trends 2024; 2(2.000): 38-45]http://www.ejmanager.com/fulltextpdf.php?mno=201035cordia macleodiidpph methodplant extractalternative medicinein vivo study |
| spellingShingle | Sajidur Rahman Akash Samia Alam Etha Md. Redowan Hossain Sonet Enamul Hoque Md. Sujunur Rahman Md. Nasir Uddin Ohidul Islam Dr. Lubna Jahan In vitro evaluation of antioxidant and antimicrobial properties of Cordia mocleodii leaf extract Plant Trends cordia macleodii dpph method plant extract alternative medicine in vivo study |
| title | In vitro evaluation of antioxidant and antimicrobial properties of Cordia mocleodii leaf extract |
| title_full | In vitro evaluation of antioxidant and antimicrobial properties of Cordia mocleodii leaf extract |
| title_fullStr | In vitro evaluation of antioxidant and antimicrobial properties of Cordia mocleodii leaf extract |
| title_full_unstemmed | In vitro evaluation of antioxidant and antimicrobial properties of Cordia mocleodii leaf extract |
| title_short | In vitro evaluation of antioxidant and antimicrobial properties of Cordia mocleodii leaf extract |
| title_sort | in vitro evaluation of antioxidant and antimicrobial properties of cordia mocleodii leaf extract |
| topic | cordia macleodii dpph method plant extract alternative medicine in vivo study |
| url | http://www.ejmanager.com/fulltextpdf.php?mno=201035 |
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