Head-to-head comparison of four cerebrospinal fluid and three plasma neurofilament light chain assays in Parkinsonism

Head-to-head comparison of four cerebrospinal fluid and three plasma neurofilament light chain assays in Parkinsonism

Abstract Neurofilament light chain protein (NfL) is a valuable biomarker for the differential diagnosis between Parkinson’s disease (PD) and atypical parkinsonian disorders (APD). Here, we compared the performance of four cerebrospinal fluid (CSF) and three plasma NfL immunoassays in 253 PD and 265...

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Main Authors: Simone Baiardi, Marcello Rossi, Giulia Giannini, Angela Mammana, Barbara Polischi, Luisa Sambati, Andrea Mastrangelo, Franco Magliocchetti, Pietro Cortelli, Sabina Capellari, Giovanna Calandra Buonaura, Piero Parchi
Format: Article
Language:English
Published: Nature Portfolio 2025-04-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-025-00951-y
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