White matter hyperintensities, executive function and global cognitive performance in vascular mild cognitive impairment
Vascular mild cognitive impairment (VaMCI) represents an early symptomatic stage of vascular cognitive impairment and might be associated to fronto-executive dysfunction. Methods Twenty-six individuals (age: 73.11±7.90 years; 65.4% female; schooling: 9.84±3.61 years) were selected through neuropsyc...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Thieme Revinter Publicações
2013-07-01
|
| Series: | Arquivos de Neuro-Psiquiatria |
| Subjects: | |
| Online Access: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2013000700431&lng=en&tlng=en |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850245971141722112 |
|---|---|
| author | Felipe Kenji Sudo Carlos Eduardo Oliveira Alves Gilberto Sousa Alves Letice Ericeira-Valente Chan Tiel Denise Madeira Moreira Jerson Laks Eliasz Engelhardt |
| author_facet | Felipe Kenji Sudo Carlos Eduardo Oliveira Alves Gilberto Sousa Alves Letice Ericeira-Valente Chan Tiel Denise Madeira Moreira Jerson Laks Eliasz Engelhardt |
| author_sort | Felipe Kenji Sudo |
| collection | DOAJ |
| description | Vascular mild cognitive impairment (VaMCI) represents an early symptomatic stage of vascular cognitive impairment and might be associated to fronto-executive dysfunction. Methods Twenty-six individuals (age: 73.11±7.90 years; 65.4% female; schooling: 9.84±3.61 years) were selected through neuropsychological assessment and neuroimaging. Clinical and neuroimaging data of VaMCI individuals (n=15) were compared to normal controls (NC, n=11) and correlated with Fazekas scale. Results VaMCI performed significantly worse than NC in Trail-Making Test (TMT) B, errors in TMT B, difference TMT B-A and Cambridge Cognitive Examination (CAMCOG) final scores. Correlations were found among scores in modified Fazekas scale and performances in TMT B (time to complete and errors), difference TMT B-A and CAMCOG total score. Conclusion Extension of white matter hyperintensities might be correlated to poorer global cognition and impairments in a set of fronto-executive functions, such as cognitive speed, set shifting and inhibitory control in VaMCI. |
| format | Article |
| id | doaj-art-0f901c52f7ec40f09fa0e7d6baf1c1de |
| institution | OA Journals |
| issn | 1678-4227 |
| language | English |
| publishDate | 2013-07-01 |
| publisher | Thieme Revinter Publicações |
| record_format | Article |
| series | Arquivos de Neuro-Psiquiatria |
| spelling | doaj-art-0f901c52f7ec40f09fa0e7d6baf1c1de2025-08-20T01:59:18ZengThieme Revinter PublicaçõesArquivos de Neuro-Psiquiatria1678-42272013-07-0171743143610.1590/0004-282X20130057S0004-282X2013000700431White matter hyperintensities, executive function and global cognitive performance in vascular mild cognitive impairmentFelipe Kenji SudoCarlos Eduardo Oliveira AlvesGilberto Sousa AlvesLetice Ericeira-ValenteChan TielDenise Madeira MoreiraJerson LaksEliasz EngelhardtVascular mild cognitive impairment (VaMCI) represents an early symptomatic stage of vascular cognitive impairment and might be associated to fronto-executive dysfunction. Methods Twenty-six individuals (age: 73.11±7.90 years; 65.4% female; schooling: 9.84±3.61 years) were selected through neuropsychological assessment and neuroimaging. Clinical and neuroimaging data of VaMCI individuals (n=15) were compared to normal controls (NC, n=11) and correlated with Fazekas scale. Results VaMCI performed significantly worse than NC in Trail-Making Test (TMT) B, errors in TMT B, difference TMT B-A and Cambridge Cognitive Examination (CAMCOG) final scores. Correlations were found among scores in modified Fazekas scale and performances in TMT B (time to complete and errors), difference TMT B-A and CAMCOG total score. Conclusion Extension of white matter hyperintensities might be correlated to poorer global cognition and impairments in a set of fronto-executive functions, such as cognitive speed, set shifting and inhibitory control in VaMCI.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2013000700431&lng=en&tlng=encomprometimento cognitivo levedemencia vascularfuncao executivaneuropsicologianeuroimagemtranstornos cerebrovasculares |
| spellingShingle | Felipe Kenji Sudo Carlos Eduardo Oliveira Alves Gilberto Sousa Alves Letice Ericeira-Valente Chan Tiel Denise Madeira Moreira Jerson Laks Eliasz Engelhardt White matter hyperintensities, executive function and global cognitive performance in vascular mild cognitive impairment Arquivos de Neuro-Psiquiatria comprometimento cognitivo leve demencia vascular funcao executiva neuropsicologia neuroimagem transtornos cerebrovasculares |
| title | White matter hyperintensities, executive function and global cognitive performance in vascular mild cognitive impairment |
| title_full | White matter hyperintensities, executive function and global cognitive performance in vascular mild cognitive impairment |
| title_fullStr | White matter hyperintensities, executive function and global cognitive performance in vascular mild cognitive impairment |
| title_full_unstemmed | White matter hyperintensities, executive function and global cognitive performance in vascular mild cognitive impairment |
| title_short | White matter hyperintensities, executive function and global cognitive performance in vascular mild cognitive impairment |
| title_sort | white matter hyperintensities executive function and global cognitive performance in vascular mild cognitive impairment |
| topic | comprometimento cognitivo leve demencia vascular funcao executiva neuropsicologia neuroimagem transtornos cerebrovasculares |
| url | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2013000700431&lng=en&tlng=en |
| work_keys_str_mv | AT felipekenjisudo whitematterhyperintensitiesexecutivefunctionandglobalcognitiveperformanceinvascularmildcognitiveimpairment AT carloseduardooliveiraalves whitematterhyperintensitiesexecutivefunctionandglobalcognitiveperformanceinvascularmildcognitiveimpairment AT gilbertosousaalves whitematterhyperintensitiesexecutivefunctionandglobalcognitiveperformanceinvascularmildcognitiveimpairment AT leticeericeiravalente whitematterhyperintensitiesexecutivefunctionandglobalcognitiveperformanceinvascularmildcognitiveimpairment AT chantiel whitematterhyperintensitiesexecutivefunctionandglobalcognitiveperformanceinvascularmildcognitiveimpairment AT denisemadeiramoreira whitematterhyperintensitiesexecutivefunctionandglobalcognitiveperformanceinvascularmildcognitiveimpairment AT jersonlaks whitematterhyperintensitiesexecutivefunctionandglobalcognitiveperformanceinvascularmildcognitiveimpairment AT eliaszengelhardt whitematterhyperintensitiesexecutivefunctionandglobalcognitiveperformanceinvascularmildcognitiveimpairment |