Chronic tophaceous gout presenting with severe hypercalcemia - A rare clinical entity
Gout is an inflammatory arthritis caused by the accumulation of monosodium urate crystals within the synovial fluid and surrounding tissues. This condition is closely linked to hyperuricaemia, a serum urate concentration of 6.8 mg/dL or higher. If hyperuricaemia is not properly managed, the disease...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2025-05-01
|
| Series: | Current Medicine Research and Practice |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/cmrp.cmrp_23_25 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850082623773212672 |
|---|---|
| author | Jagmeet Singh Rohit Raina Ishan Garg Vikas Garg |
| author_facet | Jagmeet Singh Rohit Raina Ishan Garg Vikas Garg |
| author_sort | Jagmeet Singh |
| collection | DOAJ |
| description | Gout is an inflammatory arthritis caused by the accumulation of monosodium urate crystals within the synovial fluid and surrounding tissues. This condition is closely linked to hyperuricaemia, a serum urate concentration of 6.8 mg/dL or higher. If hyperuricaemia is not properly managed, the disease may progress to chronic tophaceous gout, which involves long-term joint damage and deposition of crystal aggregates (tophi) in joints and soft tissues. In this case report, we describe the case of a 62-year-old male who presented with altered mental status, generalised weakness, poor oral intake and diffuse body pain. Laboratory tests revealed severe hypercalcaemia, which is a rare presentation. The patient was treated with intravenous saline hydration, calcitonin and prednisone, which improved kidney function and normalised calcium levels. |
| format | Article |
| id | doaj-art-0f8a8a6968944674bcad36cb6eeb982d |
| institution | DOAJ |
| issn | 2352-0817 2352-0825 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Current Medicine Research and Practice |
| spelling | doaj-art-0f8a8a6968944674bcad36cb6eeb982d2025-08-20T02:44:29ZengWolters Kluwer Medknow PublicationsCurrent Medicine Research and Practice2352-08172352-08252025-05-0115311211410.4103/cmrp.cmrp_23_25Chronic tophaceous gout presenting with severe hypercalcemia - A rare clinical entityJagmeet SinghRohit RainaIshan GargVikas GargGout is an inflammatory arthritis caused by the accumulation of monosodium urate crystals within the synovial fluid and surrounding tissues. This condition is closely linked to hyperuricaemia, a serum urate concentration of 6.8 mg/dL or higher. If hyperuricaemia is not properly managed, the disease may progress to chronic tophaceous gout, which involves long-term joint damage and deposition of crystal aggregates (tophi) in joints and soft tissues. In this case report, we describe the case of a 62-year-old male who presented with altered mental status, generalised weakness, poor oral intake and diffuse body pain. Laboratory tests revealed severe hypercalcaemia, which is a rare presentation. The patient was treated with intravenous saline hydration, calcitonin and prednisone, which improved kidney function and normalised calcium levels.https://journals.lww.com/10.4103/cmrp.cmrp_23_25gouthypercalcemiahyperuricaemiapolyarticulartophi |
| spellingShingle | Jagmeet Singh Rohit Raina Ishan Garg Vikas Garg Chronic tophaceous gout presenting with severe hypercalcemia - A rare clinical entity Current Medicine Research and Practice gout hypercalcemia hyperuricaemia polyarticular tophi |
| title | Chronic tophaceous gout presenting with severe hypercalcemia - A rare clinical entity |
| title_full | Chronic tophaceous gout presenting with severe hypercalcemia - A rare clinical entity |
| title_fullStr | Chronic tophaceous gout presenting with severe hypercalcemia - A rare clinical entity |
| title_full_unstemmed | Chronic tophaceous gout presenting with severe hypercalcemia - A rare clinical entity |
| title_short | Chronic tophaceous gout presenting with severe hypercalcemia - A rare clinical entity |
| title_sort | chronic tophaceous gout presenting with severe hypercalcemia a rare clinical entity |
| topic | gout hypercalcemia hyperuricaemia polyarticular tophi |
| url | https://journals.lww.com/10.4103/cmrp.cmrp_23_25 |
| work_keys_str_mv | AT jagmeetsingh chronictophaceousgoutpresentingwithseverehypercalcemiaarareclinicalentity AT rohitraina chronictophaceousgoutpresentingwithseverehypercalcemiaarareclinicalentity AT ishangarg chronictophaceousgoutpresentingwithseverehypercalcemiaarareclinicalentity AT vikasgarg chronictophaceousgoutpresentingwithseverehypercalcemiaarareclinicalentity |