Efficacy of amifostine in protection against doxorubicin-induced acute cardiotoxic effects in rats

Efficacy of amifostine in protection against doxorubicin-induced acute cardiotoxic effects in rats

Background/Aim. Amifostine (AMI) is a broad-spectrum cytoprotector which protects against variety of radio- and chemotherapy-related toxicities without decreasing their antitumor action. The aim of the study was to investigate the potential protective effects of AMI against acute cardiotoxic eff...

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Bibliographic Details
Main Authors: Dragojević-Simić Viktorija, Dobrić Silva, Jaćević Vesna, Bokonjić Dubravko, Milosavljević Ivica, Kovačević Aleksandra, Mikić Dragan
Format: Article
Language:English
Published: Ministry of Defence of the Republic of Serbia, University of Defence, Belgrade 2013-01-01
Series:Vojnosanitetski Pregled
Subjects:
amifostine
doxorubicin
heart drug toxicity
cytoprotection
rats
wistar
Online Access:http://www.doiserbia.nb.rs/img/doi/0042-8450/2013/0042-84501200041D.pdf
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