Dual-site phosphorylation of the control of virulence regulator impacts group a streptococcal global gene expression and pathogenesis.

Dual-site phosphorylation of the control of virulence regulator impacts group a streptococcal global gene expression and pathogenesis.

Phosphorylation relays are a major mechanism by which bacteria alter transcription in response to environmental signals, but understanding of the functional consequences of bacterial response regulator phosphorylation is limited. We sought to characterize how phosphorylation of the control of virule...

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Bibliographic Details
Main Authors: Nicola Horstmann, Miguel Saldaña, Pranoti Sahasrabhojane, Hui Yao, Xiaoping Su, Erika Thompson, Antonius Koller, Samuel A Shelburne
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-05-01
Series:PLoS Pathogens
Online Access:https://journals.plos.org/plospathogens/article/file?id=10.1371/journal.ppat.1004088&type=printable
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