Aggressive Cardiac Involvement in Systemic Lupus Erythematosus: A Case Report and a Comprehensive Literature Review
Background. We present the case of a 35-year-old gentleman who presented with an aggressive cardiomyopathy with normal coronary arteries. He was later diagnosed with systemic lupus-related cardiomyopathy. Methods. We undertook an extensive review of the literature regarding cardiac manifestations of...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | Cardiology Research and Practice |
| Online Access: | http://dx.doi.org/10.4061/2011/578390 |
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| _version_ | 1832561197940998144 |
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| author | Reza Ashrafi Pankaj Garg Ewan McKay John Gosney Som Chuah Gershan Davis |
| author_facet | Reza Ashrafi Pankaj Garg Ewan McKay John Gosney Som Chuah Gershan Davis |
| author_sort | Reza Ashrafi |
| collection | DOAJ |
| description | Background. We present the case of a 35-year-old gentleman who presented with an aggressive cardiomyopathy with normal coronary arteries. He was later diagnosed with systemic lupus-related cardiomyopathy. Methods. We undertook an extensive review of the literature regarding cardiac manifestations of lupus and used over 100 journals to identify the key points in pathology, diagnosis, and treatment. Results. We have shown that cardiac lupus can be rapidly progressive and, unless treated early, can have severe consequences. The predominant pathologies are immune complex and accelerated atherosclerosis drive. Treatment comprised of high-level immunosuppression. |
| format | Article |
| id | doaj-art-0f819ef26bcf45eb9cd862fe04eac0b1 |
| institution | Kabale University |
| issn | 2090-0597 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Cardiology Research and Practice |
| spelling | doaj-art-0f819ef26bcf45eb9cd862fe04eac0b12025-02-03T01:25:40ZengWileyCardiology Research and Practice2090-05972011-01-01201110.4061/2011/578390578390Aggressive Cardiac Involvement in Systemic Lupus Erythematosus: A Case Report and a Comprehensive Literature ReviewReza Ashrafi0Pankaj Garg1Ewan McKay2John Gosney3Som Chuah4Gershan Davis5Aintree Cardiac Centre, University Hospital Aintree, Lower Lane, Liverpool L9 7AL, UKAintree Cardiac Centre, University Hospital Aintree, Lower Lane, Liverpool L9 7AL, UKAintree Cardiac Centre, University Hospital Aintree, Lower Lane, Liverpool L9 7AL, UKDepartment of Pathology, The Royal Liverpool University Hospital, Prescot Street, Liverpool L7 8XP, UKAintree Cardiac Centre, University Hospital Aintree, Lower Lane, Liverpool L9 7AL, UKAintree Cardiac Centre, University Hospital Aintree, Lower Lane, Liverpool L9 7AL, UKBackground. We present the case of a 35-year-old gentleman who presented with an aggressive cardiomyopathy with normal coronary arteries. He was later diagnosed with systemic lupus-related cardiomyopathy. Methods. We undertook an extensive review of the literature regarding cardiac manifestations of lupus and used over 100 journals to identify the key points in pathology, diagnosis, and treatment. Results. We have shown that cardiac lupus can be rapidly progressive and, unless treated early, can have severe consequences. The predominant pathologies are immune complex and accelerated atherosclerosis drive. Treatment comprised of high-level immunosuppression.http://dx.doi.org/10.4061/2011/578390 |
| spellingShingle | Reza Ashrafi Pankaj Garg Ewan McKay John Gosney Som Chuah Gershan Davis Aggressive Cardiac Involvement in Systemic Lupus Erythematosus: A Case Report and a Comprehensive Literature Review Cardiology Research and Practice |
| title | Aggressive Cardiac Involvement in Systemic Lupus Erythematosus: A Case Report and a Comprehensive Literature Review |
| title_full | Aggressive Cardiac Involvement in Systemic Lupus Erythematosus: A Case Report and a Comprehensive Literature Review |
| title_fullStr | Aggressive Cardiac Involvement in Systemic Lupus Erythematosus: A Case Report and a Comprehensive Literature Review |
| title_full_unstemmed | Aggressive Cardiac Involvement in Systemic Lupus Erythematosus: A Case Report and a Comprehensive Literature Review |
| title_short | Aggressive Cardiac Involvement in Systemic Lupus Erythematosus: A Case Report and a Comprehensive Literature Review |
| title_sort | aggressive cardiac involvement in systemic lupus erythematosus a case report and a comprehensive literature review |
| url | http://dx.doi.org/10.4061/2011/578390 |
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