Vitamin D-deficient rickets mimicking ankylosing spondylitis in an adolescent girl
Vitamin D-deficient rickets (VDDR) remains an important health problem especially in developing countries. Insufficient dietary intake of vitamin D and inadequate sun exposure increase the risk of vitamin D deficiency. Since their vitamin D requirement is increased, children and adolescents a...
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| Format: | Article |
| Language: | English |
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Hacettepe University Institute of Child Health
2012-04-01
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| Series: | The Turkish Journal of Pediatrics |
| Online Access: | https://turkjpediatr.org/article/view/1615 |
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| author | Hüseyin Demirbilek Didem Aydoğdu Alev Ozön |
| author_facet | Hüseyin Demirbilek Didem Aydoğdu Alev Ozön |
| author_sort | Hüseyin Demirbilek |
| collection | DOAJ |
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Vitamin D-deficient rickets (VDDR) remains an important health problem especially in developing countries. Insufficient dietary intake of vitamin D and inadequate sun exposure increase the risk of vitamin D deficiency. Since their vitamin D requirement is increased, children and adolescents are potentially at higher risk for vitamin D deficiency. In adolescents, vitamin D deficiency causes osteomalacia, osteoporosis and muscle weakness. While osteoporosis is not associated with bone pain, osteomalacia has been associated with isolated or generalized bone pain. The present case suffered from generalized bone pain for three years. She was misdiagnosed as ankylosing spondylitis, which is a seronegative arthropathy, and was treated with corticosteroids and methotrexate, which have potential side effects. Hypocalcemia, hypophosphatemia, elevated alkaline phosphatase level, secondary hyperparathyroidism, and extremely low vitamin D level were consistent with the diagnosis of severe vitamin D deficiency. Complete clinical and biochemical resolution was achieved with vitamin D replacement.
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| format | Article |
| id | doaj-art-0f800b71dc9d4159ae76218be7950d14 |
| institution | DOAJ |
| issn | 0041-4301 2791-6421 |
| language | English |
| publishDate | 2012-04-01 |
| publisher | Hacettepe University Institute of Child Health |
| record_format | Article |
| series | The Turkish Journal of Pediatrics |
| spelling | doaj-art-0f800b71dc9d4159ae76218be7950d142025-08-20T02:55:39ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212012-04-01542Vitamin D-deficient rickets mimicking ankylosing spondylitis in an adolescent girlHüseyin Demirbilek0Didem AydoğduAlev OzönDivision of Paediatric Endocrinology, Hacettepe University Faculty of Medicine, Ankara, Turkey. Vitamin D-deficient rickets (VDDR) remains an important health problem especially in developing countries. Insufficient dietary intake of vitamin D and inadequate sun exposure increase the risk of vitamin D deficiency. Since their vitamin D requirement is increased, children and adolescents are potentially at higher risk for vitamin D deficiency. In adolescents, vitamin D deficiency causes osteomalacia, osteoporosis and muscle weakness. While osteoporosis is not associated with bone pain, osteomalacia has been associated with isolated or generalized bone pain. The present case suffered from generalized bone pain for three years. She was misdiagnosed as ankylosing spondylitis, which is a seronegative arthropathy, and was treated with corticosteroids and methotrexate, which have potential side effects. Hypocalcemia, hypophosphatemia, elevated alkaline phosphatase level, secondary hyperparathyroidism, and extremely low vitamin D level were consistent with the diagnosis of severe vitamin D deficiency. Complete clinical and biochemical resolution was achieved with vitamin D replacement. https://turkjpediatr.org/article/view/1615 |
| spellingShingle | Hüseyin Demirbilek Didem Aydoğdu Alev Ozön Vitamin D-deficient rickets mimicking ankylosing spondylitis in an adolescent girl The Turkish Journal of Pediatrics |
| title | Vitamin D-deficient rickets mimicking ankylosing spondylitis in an adolescent girl |
| title_full | Vitamin D-deficient rickets mimicking ankylosing spondylitis in an adolescent girl |
| title_fullStr | Vitamin D-deficient rickets mimicking ankylosing spondylitis in an adolescent girl |
| title_full_unstemmed | Vitamin D-deficient rickets mimicking ankylosing spondylitis in an adolescent girl |
| title_short | Vitamin D-deficient rickets mimicking ankylosing spondylitis in an adolescent girl |
| title_sort | vitamin d deficient rickets mimicking ankylosing spondylitis in an adolescent girl |
| url | https://turkjpediatr.org/article/view/1615 |
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