GFP-on mouse model for interrogation of in vivo gene editing

GFP-on mouse model for interrogation of in vivo gene editing

Abstract Gene editing technologies have revolutionized therapies for numerous genetic diseases. However, in vivo gene editing hinges on identifying efficient delivery vehicles for editing in targeted cell types, a significant hurdle in fully realizing its therapeutic potential. A model system to rap...

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Main Authors: Carla Dib, Jack A. Queenan, Leah Swartzrock, Hana Willner, Morgane Denis, Nouraiz Ahmed, Fareha Moulana Zada, Beltran Borges, Carsten T. Charlesworth, Tony Lum, Bradley P. Yates, Caleb Y. Kwon, Augustino V. Scorzo, Scott C. Davis, Jessie R. Davis, Ran He, Jun Xie, Guangping Gao, Tippi C. MacKenzie, David R. Liu, Gregory A. Newby, Agnieszka D. Czechowicz
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-61449-y
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