Haematological and haemodynamic changes in hypovolemic dogs
In this study, same haematological and haemodynamic changes in hypovolemic dogs were investigated. For this purpose totally 20 dogs were usedas a material. The dogs were anesthetized with thiopenthal sodium (30 mg/kg iv), and the n haemorrhagic shock was performed experimentally. The mean arterial p...
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Selcuk University Press
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| Series: | Eurasian Journal of Veterinary Sciences |
| Online Access: | http://eurasianjvetsci.org/pdf.php3?id=790 |
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| author | Ercan Keskin Mursayettin Eksen |
| author_facet | Ercan Keskin Mursayettin Eksen |
| author_sort | Ercan Keskin |
| collection | DOAJ |
| description | In this study, same haematological and
haemodynamic changes in hypovolemic dogs were investigated. For this purpose totally 20 dogs were usedas a material. The dogs were anesthetized with thiopenthal sodium (30 mg/kg iv), and the n haemorrhagic shock was performed experimentally. The mean arterial pressure (MAP)
was reduced to 40±5 mmHg and maintained at this level for 30 min (Hypotensive period).<p>
The blood samples for the determinatfon of hemogram and blood gases analyses were taken before the experiment and at the e nd of the hypotensive period and other paramaters were recorded.<p>
Be fare the experiment the me an alterfal press u re (MAP), the mean systo/ic arterfal pressure (MSAP) and the mean diastolic arterfal pressure (MDAP) were found to be 120. 7, 151.4 and 105.4 mmHg, respectively. These values were found to be 41.5, 54. 0 and 35.3 mmHg at the end of the
hypotensive period, respectevely. On the other hand, before the experiment while the mean heart rate and the mean respiration rate were found to be 64.3 and 15. 6, the same values were determined to be 102.2 and 33 at the and of the hypotensive period, respective!y.<p>
At the and of the hypotensive period, the mean values of WBC, haematocrft and haemog!obin levels decreased drastical!y when they were compared with the levels before the experiment.<p>
At the en d of the hypotensive period, ap H and vpH, aHCO<sub>3</sub>
and vHCO<sub>3</sub>, apCO<sub>2</sub> atCO<sub>2</sub> and vtCO<sub>2</sub>, vo<sub>2</sub> saturation,
aO<sub>2</sub> and vO<sub>2</sub> concentration !eve/s decreased. On the other
h and, at the e nd of the hypotensive period the mean arterial base excess (aBE) and venous base excess (vBE) levels decreased drastically. |
| format | Article |
| id | doaj-art-0f6d4e6d2dbf49cd877d8eb777c186ff |
| institution | Kabale University |
| issn | 1309-6958 2146-1953 |
| language | English |
| publisher | Selcuk University Press |
| record_format | Article |
| series | Eurasian Journal of Veterinary Sciences |
| spelling | doaj-art-0f6d4e6d2dbf49cd877d8eb777c186ff2025-02-03T11:31:18ZengSelcuk University PressEurasian Journal of Veterinary Sciences1309-69582146-1953921519790Haematological and haemodynamic changes in hypovolemic dogsErcan Keskin0Mursayettin Eksen1Dr. Araş. Gör., S.Ü. Veteriner Fakültesi Fizyoloji Anabilimdalı, KonyaYrd. Doç. Dr., S.Ü. Veteriner Fakültesi Fizyoloji Anabilimdalı, KonyaIn this study, same haematological and haemodynamic changes in hypovolemic dogs were investigated. For this purpose totally 20 dogs were usedas a material. The dogs were anesthetized with thiopenthal sodium (30 mg/kg iv), and the n haemorrhagic shock was performed experimentally. The mean arterial pressure (MAP) was reduced to 40±5 mmHg and maintained at this level for 30 min (Hypotensive period).<p> The blood samples for the determinatfon of hemogram and blood gases analyses were taken before the experiment and at the e nd of the hypotensive period and other paramaters were recorded.<p> Be fare the experiment the me an alterfal press u re (MAP), the mean systo/ic arterfal pressure (MSAP) and the mean diastolic arterfal pressure (MDAP) were found to be 120. 7, 151.4 and 105.4 mmHg, respectively. These values were found to be 41.5, 54. 0 and 35.3 mmHg at the end of the hypotensive period, respectevely. On the other hand, before the experiment while the mean heart rate and the mean respiration rate were found to be 64.3 and 15. 6, the same values were determined to be 102.2 and 33 at the and of the hypotensive period, respective!y.<p> At the and of the hypotensive period, the mean values of WBC, haematocrft and haemog!obin levels decreased drastical!y when they were compared with the levels before the experiment.<p> At the en d of the hypotensive period, ap H and vpH, aHCO<sub>3</sub> and vHCO<sub>3</sub>, apCO<sub>2</sub> atCO<sub>2</sub> and vtCO<sub>2</sub>, vo<sub>2</sub> saturation, aO<sub>2</sub> and vO<sub>2</sub> concentration !eve/s decreased. On the other h and, at the e nd of the hypotensive period the mean arterial base excess (aBE) and venous base excess (vBE) levels decreased drastically.http://eurasianjvetsci.org/pdf.php3?id=790 |
| spellingShingle | Ercan Keskin Mursayettin Eksen Haematological and haemodynamic changes in hypovolemic dogs Eurasian Journal of Veterinary Sciences |
| title | Haematological and haemodynamic changes in hypovolemic dogs |
| title_full | Haematological and haemodynamic changes in hypovolemic dogs |
| title_fullStr | Haematological and haemodynamic changes in hypovolemic dogs |
| title_full_unstemmed | Haematological and haemodynamic changes in hypovolemic dogs |
| title_short | Haematological and haemodynamic changes in hypovolemic dogs |
| title_sort | haematological and haemodynamic changes in hypovolemic dogs |
| url | http://eurasianjvetsci.org/pdf.php3?id=790 |
| work_keys_str_mv | AT ercankeskin haematologicalandhaemodynamicchangesinhypovolemicdogs AT mursayettineksen haematologicalandhaemodynamicchangesinhypovolemicdogs |