Postimplantation syndrome following stentless thoracic endovascular aortic repair of chronic aortic dissection

Postimplantation syndrome (PIS) is a noninfectious systemic inflammatory response that often follows endovascular aneurysm repair, historically presumed to be a reaction to implanted graft materials. Although well-documented with stent graft use, PIS in the absence of stent grafts remains poorly und...

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Main Authors: Justin Blackman, MS, Brandon McGuinness, MSc, MD, Vamshi K. Kotha, MD
Format: Article
Language:English
Published: Elsevier 2025-10-01
Series:Journal of Vascular Surgery Cases and Innovative Techniques
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Online Access:http://www.sciencedirect.com/science/article/pii/S2468428725002151
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author Justin Blackman, MS
Brandon McGuinness, MSc, MD
Vamshi K. Kotha, MD
author_facet Justin Blackman, MS
Brandon McGuinness, MSc, MD
Vamshi K. Kotha, MD
author_sort Justin Blackman, MS
collection DOAJ
description Postimplantation syndrome (PIS) is a noninfectious systemic inflammatory response that often follows endovascular aneurysm repair, historically presumed to be a reaction to implanted graft materials. Although well-documented with stent graft use, PIS in the absence of stent grafts remains poorly understood. We present an instance of PIS after stentless thoracic endovascular aortic repair, which involves embolizing intimal tears with plugs and/or coils. This case highlights the need for further investigation into the pathophysiology of PIS. PIS can occur in the absence of a stent graft; prophylactic anti-inflammatory therapy may be warranted during endovascular interventions with large-volume aneurysms or false lumen thrombosis.
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series Journal of Vascular Surgery Cases and Innovative Techniques
spelling doaj-art-0f68f75e2bdb4f3ebc26d162840080372025-08-23T04:48:48ZengElsevierJournal of Vascular Surgery Cases and Innovative Techniques2468-42872025-10-0111510193310.1016/j.jvscit.2025.101933Postimplantation syndrome following stentless thoracic endovascular aortic repair of chronic aortic dissectionJustin Blackman, MS0Brandon McGuinness, MSc, MD1Vamshi K. Kotha, MD2Island Medical Program, Faculty of Medicine, University of British Columbia, University of Victoria, Victoria, British Columbia, Canada; Correspondence: Justin Blackman, MS, University of Victoria, PO Box 1700 STN CSC, Victoria, British Columbia, V8W 2Y2Island Medical Program, Faculty of Medicine, University of British Columbia, University of Victoria, Victoria, British Columbia, Canada; Department of Vascular Surgery, Vancouver Island Health Authority, Victoria, British Columbia, CanadaSouth Island Medical Imaging, Vancouver Island Health Authority, Victoria, British Columbia, CanadaPostimplantation syndrome (PIS) is a noninfectious systemic inflammatory response that often follows endovascular aneurysm repair, historically presumed to be a reaction to implanted graft materials. Although well-documented with stent graft use, PIS in the absence of stent grafts remains poorly understood. We present an instance of PIS after stentless thoracic endovascular aortic repair, which involves embolizing intimal tears with plugs and/or coils. This case highlights the need for further investigation into the pathophysiology of PIS. PIS can occur in the absence of a stent graft; prophylactic anti-inflammatory therapy may be warranted during endovascular interventions with large-volume aneurysms or false lumen thrombosis.http://www.sciencedirect.com/science/article/pii/S2468428725002151Postimplantation syndromeTEVAREndovascular repairAortic dissectionSystemic inflammatory responseCorticosteroids
spellingShingle Justin Blackman, MS
Brandon McGuinness, MSc, MD
Vamshi K. Kotha, MD
Postimplantation syndrome following stentless thoracic endovascular aortic repair of chronic aortic dissection
Journal of Vascular Surgery Cases and Innovative Techniques
Postimplantation syndrome
TEVAR
Endovascular repair
Aortic dissection
Systemic inflammatory response
Corticosteroids
title Postimplantation syndrome following stentless thoracic endovascular aortic repair of chronic aortic dissection
title_full Postimplantation syndrome following stentless thoracic endovascular aortic repair of chronic aortic dissection
title_fullStr Postimplantation syndrome following stentless thoracic endovascular aortic repair of chronic aortic dissection
title_full_unstemmed Postimplantation syndrome following stentless thoracic endovascular aortic repair of chronic aortic dissection
title_short Postimplantation syndrome following stentless thoracic endovascular aortic repair of chronic aortic dissection
title_sort postimplantation syndrome following stentless thoracic endovascular aortic repair of chronic aortic dissection
topic Postimplantation syndrome
TEVAR
Endovascular repair
Aortic dissection
Systemic inflammatory response
Corticosteroids
url http://www.sciencedirect.com/science/article/pii/S2468428725002151
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