Cost-Effective Manufacturing of Microfluidics Through the Utilization of Direct Ink Writing

Microfluidics is essential for precise manipulation of fluids in small channels. However, conventional manufacturing processes for microfluidic devices are expensive, time-consuming, and require specialized equipment in a clean room. While recent studies have improved the cost-effectiveness of this...

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Main Authors: Stefanus H. Prajitna, Christian Harito, Brian Yuliarto
Format: Article
Language:English
Published: Ital Publication 2025-02-01
Series:Emerging Science Journal
Subjects:
Online Access:https://ijournalse.org/index.php/ESJ/article/view/2631
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author Stefanus H. Prajitna
Christian Harito
Brian Yuliarto
author_facet Stefanus H. Prajitna
Christian Harito
Brian Yuliarto
author_sort Stefanus H. Prajitna
collection DOAJ
description Microfluidics is essential for precise manipulation of fluids in small channels. However, conventional manufacturing processes for microfluidic devices are expensive, time-consuming, and require specialized equipment in a clean room. While recent studies have improved the cost-effectiveness of this device, there is still a need for further advancement in cost efficiency. Therefore, this study aimed to develop a custom-built direct-ink writing (DIW) printer for manufacturing microfluidic devices that is more affordable. Custom-built DIW directly printed microfluidic channels onto microscope slide glass using RTV (Room Temperature Vulcanizing) silicone sealant. To finish the microfluidics manufacturing, the printed channel will be assembled by placing the same glass on top of the printed layer. This method eliminated the need for polydimethylsiloxane (PDMS) molds and casting processes that were still found in recent studies. This innovative $250 (USD) custom-built DIW method takes 15 seconds to print microfluidics channels and showed a significant cost reduction, with each microfluidics device costing only $0.071 (USD) compared to $0.90 (USD) in previous studies. This study makes microfluidics more affordable and accessible for biomedical use.   Doi: 10.28991/ESJ-2025-09-01-01 Full Text: PDF
format Article
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institution Kabale University
issn 2610-9182
language English
publishDate 2025-02-01
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series Emerging Science Journal
spelling doaj-art-0f581087849849a48abcf75c6f2f3f362025-02-08T14:26:26ZengItal PublicationEmerging Science Journal2610-91822025-02-019111110.28991/ESJ-2025-09-01-01761Cost-Effective Manufacturing of Microfluidics Through the Utilization of Direct Ink WritingStefanus H. Prajitna0Christian Harito1Brian Yuliarto2Industrial Engineering Department, BINUS Graduate Program-Master of Industrial Engineering, Bina Nusantara University, Jakarta 11480,Industrial Engineering Department, BINUS Graduate Program-Master of Industrial Engineering, Bina Nusantara University, Jakarta 11480,Advanced Functional Material Laboratory, Engineering Physics Department, Institut Teknologi Bandung, Jl. Ganesha, 10, Bandung 40132,Microfluidics is essential for precise manipulation of fluids in small channels. However, conventional manufacturing processes for microfluidic devices are expensive, time-consuming, and require specialized equipment in a clean room. While recent studies have improved the cost-effectiveness of this device, there is still a need for further advancement in cost efficiency. Therefore, this study aimed to develop a custom-built direct-ink writing (DIW) printer for manufacturing microfluidic devices that is more affordable. Custom-built DIW directly printed microfluidic channels onto microscope slide glass using RTV (Room Temperature Vulcanizing) silicone sealant. To finish the microfluidics manufacturing, the printed channel will be assembled by placing the same glass on top of the printed layer. This method eliminated the need for polydimethylsiloxane (PDMS) molds and casting processes that were still found in recent studies. This innovative $250 (USD) custom-built DIW method takes 15 seconds to print microfluidics channels and showed a significant cost reduction, with each microfluidics device costing only $0.071 (USD) compared to $0.90 (USD) in previous studies. This study makes microfluidics more affordable and accessible for biomedical use.   Doi: 10.28991/ESJ-2025-09-01-01 Full Text: PDFhttps://ijournalse.org/index.php/ESJ/article/view/2631microfluidicsrtv siliconedirect ink writingparticle separationblood separationimage processing.
spellingShingle Stefanus H. Prajitna
Christian Harito
Brian Yuliarto
Cost-Effective Manufacturing of Microfluidics Through the Utilization of Direct Ink Writing
Emerging Science Journal
microfluidics
rtv silicone
direct ink writing
particle separation
blood separation
image processing.
title Cost-Effective Manufacturing of Microfluidics Through the Utilization of Direct Ink Writing
title_full Cost-Effective Manufacturing of Microfluidics Through the Utilization of Direct Ink Writing
title_fullStr Cost-Effective Manufacturing of Microfluidics Through the Utilization of Direct Ink Writing
title_full_unstemmed Cost-Effective Manufacturing of Microfluidics Through the Utilization of Direct Ink Writing
title_short Cost-Effective Manufacturing of Microfluidics Through the Utilization of Direct Ink Writing
title_sort cost effective manufacturing of microfluidics through the utilization of direct ink writing
topic microfluidics
rtv silicone
direct ink writing
particle separation
blood separation
image processing.
url https://ijournalse.org/index.php/ESJ/article/view/2631
work_keys_str_mv AT stefanushprajitna costeffectivemanufacturingofmicrofluidicsthroughtheutilizationofdirectinkwriting
AT christianharito costeffectivemanufacturingofmicrofluidicsthroughtheutilizationofdirectinkwriting
AT brianyuliarto costeffectivemanufacturingofmicrofluidicsthroughtheutilizationofdirectinkwriting