Application of CRISPR/Cas gene editing for infectious disease control in poultry
The poultry industry faces multifaceted challenges, including escalating demand for poultry products, climate change impacting feed availability, emergence of novel avian pathogens, and antimicrobial resistance. Traditional disease control measures are costly and not always effective, prompting the...
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| Format: | Article |
| Language: | English |
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De Gruyter
2025-05-01
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| Series: | Open Life Sciences |
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| Online Access: | https://doi.org/10.1515/biol-2025-1095 |
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| author | Gallala Mahdi |
| author_facet | Gallala Mahdi |
| author_sort | Gallala Mahdi |
| collection | DOAJ |
| description | The poultry industry faces multifaceted challenges, including escalating demand for poultry products, climate change impacting feed availability, emergence of novel avian pathogens, and antimicrobial resistance. Traditional disease control measures are costly and not always effective, prompting the need for complementary methods. Gene editing (GE, also called genome editing) technologies, particularly CRISPR/Cas9, offer promising solutions. This article summarizes recent advancements in utilizing CRISPR/Cas GE to enhance infectious disease control in poultry. It begins with an overview of modern GE techniques, highlighting CRISPR/Cas9’s advantages over other methods. The potential applications of CRISPR/Cas in poultry infectious disease prevention and control are explored, including the engineering of innovative vaccines, the generation of disease-resilient birds, and in vivo pathogen targeting. Additionally, insights are provided regarding regulatory frameworks and future perspectives in this rapidly evolving field. |
| format | Article |
| id | doaj-art-0f53dec028b8411cb740935d774bc8d0 |
| institution | Kabale University |
| issn | 2391-5412 |
| language | English |
| publishDate | 2025-05-01 |
| publisher | De Gruyter |
| record_format | Article |
| series | Open Life Sciences |
| spelling | doaj-art-0f53dec028b8411cb740935d774bc8d02025-08-20T03:48:23ZengDe GruyterOpen Life Sciences2391-54122025-05-01201p. 25810.1515/biol-2025-1095Application of CRISPR/Cas gene editing for infectious disease control in poultryGallala Mahdi0Animal Resources Department, Ministry of Municipality, Doha, State of QatarThe poultry industry faces multifaceted challenges, including escalating demand for poultry products, climate change impacting feed availability, emergence of novel avian pathogens, and antimicrobial resistance. Traditional disease control measures are costly and not always effective, prompting the need for complementary methods. Gene editing (GE, also called genome editing) technologies, particularly CRISPR/Cas9, offer promising solutions. This article summarizes recent advancements in utilizing CRISPR/Cas GE to enhance infectious disease control in poultry. It begins with an overview of modern GE techniques, highlighting CRISPR/Cas9’s advantages over other methods. The potential applications of CRISPR/Cas in poultry infectious disease prevention and control are explored, including the engineering of innovative vaccines, the generation of disease-resilient birds, and in vivo pathogen targeting. Additionally, insights are provided regarding regulatory frameworks and future perspectives in this rapidly evolving field.https://doi.org/10.1515/biol-2025-1095gene editingcrispr/caspoultryinfectious disease prevention and controlvaccinesdisease-resilience |
| spellingShingle | Gallala Mahdi Application of CRISPR/Cas gene editing for infectious disease control in poultry Open Life Sciences gene editing crispr/cas poultry infectious disease prevention and control vaccines disease-resilience |
| title | Application of CRISPR/Cas gene editing for infectious disease control in poultry |
| title_full | Application of CRISPR/Cas gene editing for infectious disease control in poultry |
| title_fullStr | Application of CRISPR/Cas gene editing for infectious disease control in poultry |
| title_full_unstemmed | Application of CRISPR/Cas gene editing for infectious disease control in poultry |
| title_short | Application of CRISPR/Cas gene editing for infectious disease control in poultry |
| title_sort | application of crispr cas gene editing for infectious disease control in poultry |
| topic | gene editing crispr/cas poultry infectious disease prevention and control vaccines disease-resilience |
| url | https://doi.org/10.1515/biol-2025-1095 |
| work_keys_str_mv | AT gallalamahdi applicationofcrisprcasgeneeditingforinfectiousdiseasecontrolinpoultry |