Molecular mechanisms and signaling pathways related to brain metastasis in breast cancer

Molecular mechanisms and signaling pathways related to brain metastasis in breast cancer

Brain metastasis in breast cancer (BCBM) significantly threatens the survival and quality of life of patients, particularly those with triple-negative (TNBC) and HER2-positive subtypes. It involves complex molecular mechanisms and diverse signaling pathways. This review highlights recent research on...

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Bibliographic Details
Main Authors: Zhuming Liang, Yanan Mo, Yujiao Zhang, Yanjing Yu, Yinan Ji
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Pharmacology
Subjects:
breast cancer
brain metastasis
molecular mechanisms
signaling pathways
immune surveillance
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2025.1585668/full
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