Clinical laboratory parameters in patients with COVID-19

Introduction: Knowing the alterations in clinical laboratory tests is useful in the diagnosis and progress of patients with COVID-19. Objective: To describe the clinical laboratory parameters in patients diagnosed with COVID-19. Methods: Descriptive study in 82 hospitalized patients with COVID-19. T...

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Main Authors: Naivy Sánchez Vera, Danay Saavedra Hernández, Carlos Jorge Hidalgo Mesa, Maykel Aguila López, Gladys Abreu Gutiérrez, Vivian Herrera González, Iliana Teresa Rodríguez García
Format: Article
Language:Spanish
Published: Editorial Ciencias Médicas - ECIMED 2021-06-01
Series:Revista Cubana de Medicina Militar
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Online Access:http://www.revmedmilitar.sld.cu/index.php/mil/article/view/1171
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author Naivy Sánchez Vera
Danay Saavedra Hernández
Carlos Jorge Hidalgo Mesa
Maykel Aguila López
Gladys Abreu Gutiérrez
Vivian Herrera González
Iliana Teresa Rodríguez García
author_facet Naivy Sánchez Vera
Danay Saavedra Hernández
Carlos Jorge Hidalgo Mesa
Maykel Aguila López
Gladys Abreu Gutiérrez
Vivian Herrera González
Iliana Teresa Rodríguez García
author_sort Naivy Sánchez Vera
collection DOAJ
description Introduction: Knowing the alterations in clinical laboratory tests is useful in the diagnosis and progress of patients with COVID-19. Objective: To describe the clinical laboratory parameters in patients diagnosed with COVID-19. Methods: Descriptive study in 82 hospitalized patients with COVID-19. The variables analyzed were age, sex, comorbidity, patient report, discharge status, hemoglobin, white blood cell count, absolute neutrophil count, absolute lymphocyte count, platelet count, erythrocyte sedimentation rate, D-dimer, creatinine, urea, alanine aminotransferase, aspartate aminotransferase, γ-glutamyl transpeptidase, alkaline phosphatase, lactate dehydrogenase, neutrophil / lymphocyte and platelet / lymphocyte ratio. Results: The average age was 55.61 ± 22.04, the majority were female (57.3%), hypertensive (41.5%), 18.3% reported serious and 14.6% died. Advanced age and comorbidity were associated with the severity report. There was a significant decrease in hemoglobin, lymphocytes; elevated erythrocyte sedimentation rate, D-dimer, creatinine, γ-glutamyl transpeptidase, and lactate dehydrogenase, especially in severe patients. The neutrophil / lymphocyte and platelet / lymphocyte ratio warned about the worsening of the patient and the possibility of death. Conclusions: The patients a mean age of 55.61, female, with arterial hypertension; they were discharged alive, reported as not serious. Mean hemoglobin values decrease, global lymphocyte count, especially in severe patients; increases D-dimer, creatinine, ALT, AST, ALP, GGT, and LD. The neutrophil / lymphocyte and platelet / lymphocyte ratio show high mean values, especially in severely ill patients and in those who died.
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spelling doaj-art-0f32c130f9574d3faf71e237179104f52025-08-20T03:55:44ZspaEditorial Ciencias Médicas - ECIMEDRevista Cubana de Medicina Militar1561-30461561-30462021-06-01502e02101171e02101171429Clinical laboratory parameters in patients with COVID-19Naivy Sánchez Vera0Danay Saavedra Hernández1Carlos Jorge Hidalgo Mesa2Maykel Aguila López3Gladys Abreu Gutiérrez4Vivian Herrera González5Iliana Teresa Rodríguez García6Hospital Miliar Manuel Fajardo Rivero, Villa ClaraCentro de Inmunología Molecular, La HabanaHospital Militar "Comandante Manuel Fajardo Rivero". Villa ClaraHospital Universitario “Arnaldo Milián Castro”. Villa ClaraHospital Militar "Comandante Manuel Fajardo Rivero". Villa ClaraHospital Militar "Comandante Manuel Fajardo Rivero". Villa ClaraHospital Militar "Comandante Manuel Fajardo Rivero". Villa ClaraIntroduction: Knowing the alterations in clinical laboratory tests is useful in the diagnosis and progress of patients with COVID-19. Objective: To describe the clinical laboratory parameters in patients diagnosed with COVID-19. Methods: Descriptive study in 82 hospitalized patients with COVID-19. The variables analyzed were age, sex, comorbidity, patient report, discharge status, hemoglobin, white blood cell count, absolute neutrophil count, absolute lymphocyte count, platelet count, erythrocyte sedimentation rate, D-dimer, creatinine, urea, alanine aminotransferase, aspartate aminotransferase, γ-glutamyl transpeptidase, alkaline phosphatase, lactate dehydrogenase, neutrophil / lymphocyte and platelet / lymphocyte ratio. Results: The average age was 55.61 ± 22.04, the majority were female (57.3%), hypertensive (41.5%), 18.3% reported serious and 14.6% died. Advanced age and comorbidity were associated with the severity report. There was a significant decrease in hemoglobin, lymphocytes; elevated erythrocyte sedimentation rate, D-dimer, creatinine, γ-glutamyl transpeptidase, and lactate dehydrogenase, especially in severe patients. The neutrophil / lymphocyte and platelet / lymphocyte ratio warned about the worsening of the patient and the possibility of death. Conclusions: The patients a mean age of 55.61, female, with arterial hypertension; they were discharged alive, reported as not serious. Mean hemoglobin values decrease, global lymphocyte count, especially in severe patients; increases D-dimer, creatinine, ALT, AST, ALP, GGT, and LD. The neutrophil / lymphocyte and platelet / lymphocyte ratio show high mean values, especially in severely ill patients and in those who died.http://www.revmedmilitar.sld.cu/index.php/mil/article/view/1171parámetros de laboratoriocovid-19sars-cov-2biomarcadores.
spellingShingle Naivy Sánchez Vera
Danay Saavedra Hernández
Carlos Jorge Hidalgo Mesa
Maykel Aguila López
Gladys Abreu Gutiérrez
Vivian Herrera González
Iliana Teresa Rodríguez García
Clinical laboratory parameters in patients with COVID-19
Revista Cubana de Medicina Militar
parámetros de laboratorio
covid-19
sars-cov-2
biomarcadores.
title Clinical laboratory parameters in patients with COVID-19
title_full Clinical laboratory parameters in patients with COVID-19
title_fullStr Clinical laboratory parameters in patients with COVID-19
title_full_unstemmed Clinical laboratory parameters in patients with COVID-19
title_short Clinical laboratory parameters in patients with COVID-19
title_sort clinical laboratory parameters in patients with covid 19
topic parámetros de laboratorio
covid-19
sars-cov-2
biomarcadores.
url http://www.revmedmilitar.sld.cu/index.php/mil/article/view/1171
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AT danaysaavedrahernandez clinicallaboratoryparametersinpatientswithcovid19
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AT maykelaguilalopez clinicallaboratoryparametersinpatientswithcovid19
AT gladysabreugutierrez clinicallaboratoryparametersinpatientswithcovid19
AT vivianherreragonzalez clinicallaboratoryparametersinpatientswithcovid19
AT ilianateresarodriguezgarcia clinicallaboratoryparametersinpatientswithcovid19