Hs-CRP levels in patients with periodontitis- a cross sectional study

Background: During the last century, cardiovascular disease (CVD) has common occurrence in most of the population and the great attendant mortality, loss of independence, impaired quality life and social and economic costs forming a compelling reason for public health concern. C reactive protein (CR...

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Main Authors: M A Shah, B K Shah, B B Modi, E B Shah, D H Dave
Format: Article
Language:English
Published: Wolters Kluwer – Medknow Publications 2015-01-01
Series:Journal of Integrated Health Sciences
Subjects:
Online Access:https://journals.lww.com/10.4103/2347-6486.238514
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author M A Shah
B K Shah
B B Modi
E B Shah
D H Dave
author_facet M A Shah
B K Shah
B B Modi
E B Shah
D H Dave
author_sort M A Shah
collection DOAJ
description Background: During the last century, cardiovascular disease (CVD) has common occurrence in most of the population and the great attendant mortality, loss of independence, impaired quality life and social and economic costs forming a compelling reason for public health concern. C reactive protein (CRP) in particular has been the focuses of attention as a key marker of atherosclerosis and elevated level constitutes a risk predictor for CVD. Aim: The present study focuses the association between periodontal inflammatory status as assessed by clinical periodontal sum score (CPSS) and levels of CRP and to co-relate periodontal destruction levels with levels of hs- CRP. Methodology: Patients with chronic generalized periodontitis were selected. Periodontal destruction of the patient included in the study was recorded by CPSS and blood was tested for hs-CRP levels. Mean, Standard deviation and range of CPSS and hs-CRP were calculated. The correlation between CPSS and hs-CRP that is clinical index and biochemical marker was made by Spearman correlation test for significant. Results: A total of 20 patients had participated in this study. The CPSS ranged from 31 to 205 and the hs-CRP levels ranged from 0.18 to 16.45. 2 tailed Spearman correlation test showed significant p value (0.05). Conclusion: Statistical significant co-relation was found between periodontal disease as assessed by CPSS and hs-CRP level. Results of this study point to the importance of diagnosing cases of severe periodontal destruction, and the need for proper health education and prompt periodontal therapy for the cases identified.
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spelling doaj-art-0f1caa61061840e4b8da0d4faab621732025-08-20T03:08:32ZengWolters Kluwer – Medknow PublicationsJournal of Integrated Health Sciences2347-64862347-64942015-01-0131152010.4103/2347-6486.238514Hs-CRP levels in patients with periodontitis- a cross sectional studyM A ShahB K ShahB B ModiE B ShahD H DaveBackground: During the last century, cardiovascular disease (CVD) has common occurrence in most of the population and the great attendant mortality, loss of independence, impaired quality life and social and economic costs forming a compelling reason for public health concern. C reactive protein (CRP) in particular has been the focuses of attention as a key marker of atherosclerosis and elevated level constitutes a risk predictor for CVD. Aim: The present study focuses the association between periodontal inflammatory status as assessed by clinical periodontal sum score (CPSS) and levels of CRP and to co-relate periodontal destruction levels with levels of hs- CRP. Methodology: Patients with chronic generalized periodontitis were selected. Periodontal destruction of the patient included in the study was recorded by CPSS and blood was tested for hs-CRP levels. Mean, Standard deviation and range of CPSS and hs-CRP were calculated. The correlation between CPSS and hs-CRP that is clinical index and biochemical marker was made by Spearman correlation test for significant. Results: A total of 20 patients had participated in this study. The CPSS ranged from 31 to 205 and the hs-CRP levels ranged from 0.18 to 16.45. 2 tailed Spearman correlation test showed significant p value (0.05). Conclusion: Statistical significant co-relation was found between periodontal disease as assessed by CPSS and hs-CRP level. Results of this study point to the importance of diagnosing cases of severe periodontal destruction, and the need for proper health education and prompt periodontal therapy for the cases identified.https://journals.lww.com/10.4103/2347-6486.238514crpcvdperiodontitisrisk factor
spellingShingle M A Shah
B K Shah
B B Modi
E B Shah
D H Dave
Hs-CRP levels in patients with periodontitis- a cross sectional study
Journal of Integrated Health Sciences
crp
cvd
periodontitis
risk factor
title Hs-CRP levels in patients with periodontitis- a cross sectional study
title_full Hs-CRP levels in patients with periodontitis- a cross sectional study
title_fullStr Hs-CRP levels in patients with periodontitis- a cross sectional study
title_full_unstemmed Hs-CRP levels in patients with periodontitis- a cross sectional study
title_short Hs-CRP levels in patients with periodontitis- a cross sectional study
title_sort hs crp levels in patients with periodontitis a cross sectional study
topic crp
cvd
periodontitis
risk factor
url https://journals.lww.com/10.4103/2347-6486.238514
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